Evaluation of Adults with Acute Viral Hepatitis A and Review of the Literature

Basit Öğe Kaydı
dc.contributor.authorTekin, R.
dc.contributor.authorYolbas, I.
dc.contributor.authorDal, T.
dc.contributor.authorDemirpence, O.
dc.contributor.authorKaya, S.
dc.contributor.authorBozkurt, F.
dc.contributor.authorDeveci, O.
dc.date.accessioned2024-04-24T17:28:21Z
dc.date.available2024-04-24T17:28:21Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractAim. In developing countries HAV infection is very common in the first years of life and it is often asymptomatic. However especially in regions of intermediate endemicity, exposure to the virus may delay and outbreaks of hepatitis A may be encountered in adults. The aim of this study is to evaluate the clinical and laboratory findings and risk factors of adults with acute viral hepatitis A. Materials and Methods. In present study we evaluated 203 patient with acute viral hepatitis A, who were admitted to four different hospitals of three cities of Turkey between January 2000-December 2011, retrospectively. The diagnosis of acute viral hepatitis A was performed by laboratory findings and clinically. Results. In a total of 203 patients, 120 (59.1%) patients were male and 83 (40.9%) were female. Mean age of cases with acute viral hepatitis A was 24.7 + 11.8 years (ranged 15 to 82 years old). Acute viral hepatitis A were seen in patient who were 15-20 years and 21-30 years old, commonly. Jaundice (74%), fatigue (68%), nausea-vomiting (56%) and dark urine (48%) were the most common symptoms in cases. Prolonged cholestasis (6.8%) was the most common atypical manifestation. Prolonged jaundice was more frequent in the cases with positive HBsAg (P<0.001). Conclusions. Acute viral hepatitis A can cause atypical presentations such as prolonged cholestasis, acute kidney injury and fulminant hepatitis. Some precautions such as routine vaccination program, improvement of hygiene conditions and informing people about it, should be taken for reducing of acute viral hepatitis A infection incidence.en_US
dc.identifier.doi10.7417/CT.2013.1634
dc.identifier.endpage541en_US
dc.identifier.issn0009-9074
dc.identifier.issn1972-6007
dc.identifier.issue6en_US
dc.identifier.pmid24424220
dc.identifier.scopus2-s2.0-84892448159
dc.identifier.scopusqualityQ2
dc.identifier.startpage537en_US
dc.identifier.urihttps://doi.org/10.7417/CT.2013.1634
dc.identifier.urihttps://hdl.handle.net/11468/20410
dc.identifier.volume164en_US
dc.identifier.wosWOS:000329935000027
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSoc Editrice Univen_US
dc.relation.ispartofClinica Terapeutica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcute Hepatitis Aen_US
dc.subjectCholestasisen_US
dc.subjectClinical Symptomsen_US
dc.subjectAtipical Presentationsen_US
dc.titleEvaluation of Adults with Acute Viral Hepatitis A and Review of the Literatureen_US
dc.titleEvaluation of Adults with Acute Viral Hepatitis A and Review of the Literature
dc.typeReview Articleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu