Hepatitis C Infection is Associated With Increased Coronary Artery Atherosclerosis Defined by Modified Reardon Severity Score System

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dc.contributor.authorAlyan, Omer
dc.contributor.authorKacmaz, Fehmi
dc.contributor.authorOzdemir, Ozean
dc.contributor.authorDeveci, Bulent
dc.contributor.authorAstan, Ramazan
dc.contributor.authorCelebi, Aksuyek Savas
dc.contributor.authorIlkay, Erdogan
dc.date.accessioned2024-04-24T17:15:03Z
dc.date.available2024-04-24T17:15:03Z
dc.date.issued2008
dc.departmentDicle Üniversitesien_US
dc.descriptionWorld Congress of Cardiology -- MAY 18-21, 2008 -- Buenos Aires, ARGENTINAen_US
dc.description.abstractBackground The link between arteriosclerotic disease in the carotid or coronary artery and chronic hepatitis C virus (HCV) infection has been shown in some studies although other studies have produced contrary results. However, the effect of chronic HCV infection on the extension or severity of coronary artery disease (CAD) has not been determined so the aim of the present study was to determine the effect of HCV infection on the severity of CAD. Methods and Results The study group comprised 139 HCV seropositive and 225 HCV seronegative patients with angiographically documented CAD. A modified scoring system of Reardon et al was used. There were no significant differences between groups in terms of sex, age, hypertension, diabetes mellitus, smoking or family history. Levels of C-reactive protein and fibrinogen were significantly hi,,her in the HCV seropositive group (p<0.001) and the Reardon severity score was higher (8.75 +/- 1.69 vs 6.01 +/- 1.80, p<0.00 1). After adjustment, HCV scropositivity still represented an independent predictor for severity of coronary atherosclerosis demonstrated by higher Reardon severity score with an odds ratio of 2.018 (95% confidence interval 1.575-2.579, p<0.00 1). Conclusion HCV infection is an independent predictor for increased coronary atherosclerosis, as demonstrated by higher Reardon severity score. (Circ J 2008; 72: 1960- 1965)en_US
dc.description.sponsorshipWorld Heart Federat,Argentine Soc Cardiol,Argentine Federat Cardiolen_US
dc.identifier.doi10.1253/circj.CJ-08-0459
dc.identifier.endpage1965en_US
dc.identifier.issn1346-9843
dc.identifier.issn1347-4820
dc.identifier.issue12en_US
dc.identifier.pmid18957787
dc.identifier.scopus2-s2.0-56849101004
dc.identifier.scopusqualityQ1
dc.identifier.startpage1960en_US
dc.identifier.urihttps://doi.org/10.1253/circj.CJ-08-0459
dc.identifier.urihttps://hdl.handle.net/11468/18317
dc.identifier.volume72en_US
dc.identifier.wosWOS:000261441300006
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherJapanese Circulation Socen_US
dc.relation.ispartofCirculation Journal
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAtherosclerosisen_US
dc.subjectHepatitis C Infectionen_US
dc.subjectInflammationen_US
dc.subjectScoringen_US
dc.titleHepatitis C Infection is Associated With Increased Coronary Artery Atherosclerosis Defined by Modified Reardon Severity Score Systemen_US
dc.titleHepatitis C Infection is Associated With Increased Coronary Artery Atherosclerosis Defined by Modified Reardon Severity Score System
dc.typeConference Objecten_US

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