Comparative study of 5% and 2.5% potassium hydroxide solution for molluscum contagiosum in children

Basit Öğe Kaydı
dc.contributor.authorUcmak, Derya
dc.contributor.authorAkkurt, Meltem Zeynep
dc.contributor.authorKacar, Seval Dogruk
dc.contributor.authorSula, Bilal
dc.contributor.authorArica, Mustafa
dc.date.accessioned2024-04-24T17:20:35Z
dc.date.available2024-04-24T17:20:35Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: Molluscum contagiosum (MC) is a pediatric viral infection that is fairly contagious. Although various treatment methods are available, the presence of facial lesions limits options of therapy. Aim: We aimed to test an alternative treatment consisting of application of two different concentrations of potassium hydroxide (of KOH 5% solution and of KOH 2.5% solution) aqueous solution. Methods: In this study we evaluated the effectiveness and side-effects of daily applications of potassium hydroxide (KOH) aqueous solution at 2.5% and 5% concentrations, twice daily in 29 children with MC. Out of a total of 29 patients with molluscum contagiosum included in the study, 13 patients in the 2.5% KOH group and 12 patients in the KOH 5% group completed the study. Families were instructed to apply potassium hydroxide twice a day. The assessment of response and side-effects were performed on days 0, 15, 30, 45 and 60 (visits were numbered 1, 2, 3, 4 and 5, respectively) and one month after. Results: We had a total of 11 (44%) patients who completely recovered after the fifth visit. While eight (66.7%) of these 11 patients were in the 5% treatment group, three (23.1%) patients were in the 2.5% treatment group, and there was a statistically meaningful difference (p<0.047). Patients with fewer lesions remitted better (p<0.05). When number of lesions were taken into consideration, difference between the two treatment groups appeared after the fourth visit (p<0.001). There were no statistical differences between the two groups with respect to side-effects (p = 0.682). Conclusions: Potassium hydroxide solution at a concentration of 5% was more effective than 2.5% in our patients. The treatment was well-tolerated on the face with the advantage of administration of lower concentrations. This study suggests potassium hydroxide may be a more preferable mode of treatment for molluscum contagiosum lesions on the face.en_US
dc.identifier.doi10.3109/15569527.2013.796479
dc.identifier.endpage59en_US
dc.identifier.issn1556-9527
dc.identifier.issn1556-9535
dc.identifier.issue1en_US
dc.identifier.pmid23713782
dc.identifier.scopus2-s2.0-84894330787
dc.identifier.scopusqualityQ3
dc.identifier.startpage54en_US
dc.identifier.urihttps://doi.org/10.3109/15569527.2013.796479
dc.identifier.urihttps://hdl.handle.net/11468/19145
dc.identifier.volume33en_US
dc.identifier.wosWOS:000331847200010
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofCutaneous and Ocular Toxicology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMolluscum Contagiosumen_US
dc.subjectPotassium Hydroxideen_US
dc.subjectTopical Applicationen_US
dc.titleComparative study of 5% and 2.5% potassium hydroxide solution for molluscum contagiosum in childrenen_US
dc.titleComparative study of 5% and 2.5% potassium hydroxide solution for molluscum contagiosum in children
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu