Improvement in cardiac structure and functions early after transcatheter closure of secundum atrial septal defect in children and adolescents

dc.contributor.authorYilmazer, Murat Muhtar
dc.contributor.authorGuven, Baris
dc.contributor.authorVupa-Cilengiroglu, Ozgul
dc.contributor.authorOner, Taliha
dc.contributor.authorDemirpence, Savas
dc.contributor.authorMese, Timur
dc.contributor.authorTavli, Vedide
dc.date.accessioned2024-04-24T17:37:32Z
dc.date.available2024-04-24T17:37:32Z
dc.date.issued2013
dc.departmentDicle Üniversitesien_US
dc.description.abstractWe sought to assess the effects of transcatheter closure of atrial septal defect (ASD) on right and left ventricular form and functions, as well as atrial volumes and pulmonary venous flows. We enrolled 25 patients (mean age: 9.02) prospectively who underwent successful transcatheter closure of secundum ASD. We performed transthoracic echocardiography, including two-dimensional, pulsed wave Doppler, M-mode echocardiography, and tissue Doppler imaging before the procedure and 1 day, 1 month, 3 months and 6 months after the procedure. Serum brain natriuretic peptide (BNP) levels were measured prior to the procedure, and 1 day, 1 month, and 3 months thereafter. Mitral inflow early diastolic wave increased significantly, while isovolumetric relaxation time and deceleration time did not change during the follow-up. The E/E'was also increased significantly during follow-up. After the closure, right ventricular size and right atrial volume reduced, while left ventricular size increased significantly. There was a statistically significant improvement in left and right ventricular Tei indices. Pulmonary vein systolic velocity and the ratio of systolic to diastolic wave decreased, while atrial reversal wave (ARW) velocity increased immediately after the procedure. Although the concentration of BNP was increased on the first day after the procedure, its levels reduced and had reached the pre-procedure values at 1 month of follow-up. In the study, a significant improvement in the right and left ventricular functions was detected after transcatheter closure of secundum ASD in the short-term follow-up. In addition, we found a significant reduction in right heart sizes with corresponding global functional improvement in the right ventricle after the procedure.en_US
dc.identifier.endpage410en_US
dc.identifier.issn0041-4301
dc.identifier.issue4en_US
dc.identifier.pmid24292034
dc.identifier.scopus2-s2.0-84888171555
dc.identifier.scopusqualityQ3
dc.identifier.startpage401en_US
dc.identifier.urihttps://hdl.handle.net/11468/20997
dc.identifier.volume55en_US
dc.identifier.wosWOS:000341414800008
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTurkish J Pediatricsen_US
dc.relation.ispartofTurkish Journal of Pediatrics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDiastolic Functionsen_US
dc.subjectTei Indexen_US
dc.subjectFilling Pressureen_US
dc.subjectCardiac Chambersen_US
dc.subjectPulmonary Venous Flowen_US
dc.titleImprovement in cardiac structure and functions early after transcatheter closure of secundum atrial septal defect in children and adolescentsen_US
dc.titleImprovement in cardiac structure and functions early after transcatheter closure of secundum atrial septal defect in children and adolescents
dc.typeArticleen_US

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