Parathyroid hormone as a marker for the differential diagnosis of acute and chronic renal failure

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dc.contributor.authorOzmen, S.
dc.contributor.authorDanis, R.
dc.contributor.authorAkin, D.
dc.contributor.authorCil, T.
dc.contributor.authorYazanel, O.
dc.date.accessioned2024-04-24T16:24:38Z
dc.date.available2024-04-24T16:24:38Z
dc.date.issued2007
dc.departmentDicle Üniversitesien_US
dc.description.abstractIt is often difficult to distinguish acute renal failure clinically from chronic renal failure, especially in patients who do not have records of their medical history. We investigated the magnitude of iPTH increase in ARF and the potential role of i1PTH as a marker for differential diagnosis of ARF and CRF in new patients referred to our renal unit. We prospectively analyzed 122 (ARF n = 64, CRF n = 58) patients referred to our renal unit with serum creatinine higher than 2 mg/dL. ROC curve analysis was performed to investigate role of iPTH for differentiating ARF from CRF. The sensitivity, specificity, and positive predictive value of iPTH in discrimination of ARF and CRF were calculated. There was no statistically significant difference regarding the means of age, sex distribution, and serum chemistry between patients with ARF or CRF. But serum iPTH (D < 0.0001) levels were lower in patients with ARF than in those with CRF. A cutoff, set at 170pg/mL for iPTH to discriminate patients with CRF, yielded a sensitivity of 88% and a specificity of 89%. This study confirms that the iPTH measurement is of clinical value in differentiating acute from chronic renal failure.en_US
dc.identifier.doi10.1080/08860220701275006
dc.identifier.endpage512en_US
dc.identifier.issn0886-022X
dc.identifier.issn1525-6049
dc.identifier.issue4en_US
dc.identifier.pmid17497477
dc.identifier.scopus2-s2.0-34248551009
dc.identifier.scopusqualityQ2
dc.identifier.startpage509en_US
dc.identifier.urihttps://doi.org/10.1080/08860220701275006
dc.identifier.urihttps://hdl.handle.net/11468/16800
dc.identifier.volume29en_US
dc.identifier.wosWOS:000246966300019
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofRenal Failure
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAcute Renal Failureen_US
dc.subjectChronic Renal Failureen_US
dc.subjectIpthen_US
dc.titleParathyroid hormone as a marker for the differential diagnosis of acute and chronic renal failureen_US
dc.titleParathyroid hormone as a marker for the differential diagnosis of acute and chronic renal failure
dc.typeArticleen_US

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