Differentiation of Tuberculous Peritonitis from Peritonitis Carcinomatosa without Surgical Intervention

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dc.contributor.authorKaya, Muhsin
dc.contributor.authorKaplan, Mehmet A.
dc.contributor.authorIsikdogan, Abdurrahman
dc.contributor.authorCelik, Yusuf
dc.date.accessioned2024-04-24T17:24:14Z
dc.date.available2024-04-24T17:24:14Z
dc.date.issued2011
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground/Aim: Ascites of tuberculous peritonitis (TBP) is an exudative type and may well be misdiagnosed as carcinomatous peritonitis, especially in the elderly. The aim of this study was to identify independent predictors that can differentiate TBP from peritonitis carcinomatosa without surgical intervention. Patients and Methods: This prospective cohort study was performed on 75 subjects in the following groups: TBP (n=27) (TBP group), ovarian cancer complicated with ascites (n=24) (Ov Ca group), and gastric cancer complicated with ascites (n=24) (Ga Ca group). The frequency of clinical symptoms, laboratory parameters, and serum tumor markers levels were compared. Results: In univariate analysis; fever, night sweats, and abdominal pain were significantly more frequent in the TBP group compared to those in the Ov Ca group (P < 0.001, P < 0.001, and P = 0.035, respectively) and the Ga Ca group (P < 0.001, P < 0.001, and P = 0.015, respectively). Serum CA 19-9 and carcino embryonic antigen (CEA) levels were significantly lower in the TBP and Ov Ca group compared to the Ga Ca group (P < 0.001 and P < 0.001, respectively). Elevated serum CA 125 level was found in all patients with TBP and Ov Ca and in 86.6% of patients with Ga Ca. In the multivariate analysis, presence of fever (P < 0.001), night sweats (P < 0.001), age under 40 years (P = 0.008), and normal serum CA 19-9 level (P = 0.044) were independent predictor of diagnosis of TBP. Conclusion: The presence of fever, elevated serum CA 125 level, normal serum CA 19-9, and CEA associated with lymphocyte predominant benign ascites may establish the diagnosis of TBP.en_US
dc.identifier.doi10.4103/1319-3767.84484
dc.identifier.endpage317en_US
dc.identifier.issn1319-3767
dc.identifier.issue5en_US
dc.identifier.pmid21912057
dc.identifier.scopus2-s2.0-80052892813
dc.identifier.scopusqualityQ2
dc.identifier.startpage312en_US
dc.identifier.urihttps://doi.org/10.4103/1319-3767.84484
dc.identifier.urihttps://hdl.handle.net/11468/19544
dc.identifier.volume17en_US
dc.identifier.wosWOS:000305196900004
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherMedknow Publications & Media Pvt Ltden_US
dc.relation.ispartofSaudi Journal of Gastroenterology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAscitesen_US
dc.subjectGastric Canceren_US
dc.subjectOvarian Canceren_US
dc.subjectPeritonitis Carcinomatosaen_US
dc.subjectTuberculous Peritonitisen_US
dc.subjectTumor Markersen_US
dc.titleDifferentiation of Tuberculous Peritonitis from Peritonitis Carcinomatosa without Surgical Interventionen_US
dc.titleDifferentiation of Tuberculous Peritonitis from Peritonitis Carcinomatosa without Surgical Intervention
dc.typeArticleen_US

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