The thiol/disulfide balance in ketone positive and ketone negative pregnant women with nausea and vomiting - A prospective study in a tertiary center

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dc.authorid0000-0002-3285-9990en_US
dc.contributor.authorEge, Serhat
dc.contributor.authorPeker, Nurullah
dc.contributor.authorBademkıran, Muhammed Hanifi
dc.contributor.authorKöçeroǧlu, Ruşen
dc.contributor.authorErel, Özcan
dc.contributor.authorErdem, Selami
dc.contributor.authorÖzgökçe, Çaǧdaş
dc.contributor.authorYıldızhan, Recep
dc.date.accessioned2021-08-25T06:06:50Z
dc.date.available2021-08-25T06:06:50Z
dc.date.issued2020en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Ana Bilim Dalıen_US
dc.description.abstractObjectives: We aimed to investigate the thiol/disulfide balance in ketone positive (hyperemesis gravidarum) and ketone negative pregnant women with nausea and vomiting. Material and methods: A total of 60 patients under the 14th week of pregnancy were included in this study, and they were divided into two groups. Group 1 included 30 pregnant women with ketone positive, group 2 included 30 ketone negative pregnant women with nausea, and vomiting. Results: The native thiol, disulfide, and total thiol concentrations were measured using an automated method and compared among the two groups. There were also three indexes that are derived from disulfide, native and total thiol (Index 1 = 100 x disulfide/native thiol); (Index 2 = 100 x disulfide/total thiol); (Index 3 = 100 x native thiol/total thiol). When compared with Group 1 and Group 2, total thiol was high, native thiol was low but not statistically significant. Disulphide (p = 0.046), index 1 (p = 0.036) and index 3 (p = 0.034) were statistically significant. Conclusions: Patients with ketone positive are shifting to OS direction due to lack of nutrients and electrolytes. This study emphasizes the therapeutic potential of antioxidant supplementation, which is becoming an increasingly used approach in treating the symptoms of women with ketone positive.en_US
dc.identifier.citationEge, S., Peker, N., Bademkıran, M. H., Köçeroǧlu, R., Erel, Ö. ve Erdem, S. (2020). The thiol/disulfide balance in ketone positive and ketone negative pregnant women with nausea and vomiting - A prospective study in a tertiary center. Ginekologia Polska, 91(4), 207-209.en_US
dc.identifier.doi10.5603/GP.A2020.0038
dc.identifier.endpage209en_US
dc.identifier.issn0017-0011
dc.identifier.issue4en_US
dc.identifier.pmid32236936
dc.identifier.scopus2-s2.0-85085952403
dc.identifier.scopusqualityQ3
dc.identifier.startpage207en_US
dc.identifier.urihttps://journals.viamedica.pl/ginekologia_polska/article/view/66704
dc.identifier.urihttps://hdl.handle.net/11468/7386
dc.identifier.volume91en_US
dc.identifier.wosWOS:000531857500007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorPeker, Nurullah
dc.language.isoenen_US
dc.publisherGIPOAen_US
dc.relation.ispartofGinekologia Polska
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHyperemesis gravidarumen_US
dc.subjectNausea and vomitingen_US
dc.subjectOxidative stressen_US
dc.subjectThiol/disulfide homeostasisen_US
dc.titleThe thiol/disulfide balance in ketone positive and ketone negative pregnant women with nausea and vomiting - A prospective study in a tertiary centeren_US
dc.titleThe thiol/disulfide balance in ketone positive and ketone negative pregnant women with nausea and vomiting - A prospective study in a tertiary center
dc.typeArticleen_US

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