Genitourinary brucellosis: results of a multicentric study

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dc.contributor.authorErdem, H.
dc.contributor.authorElaldi, N.
dc.contributor.authorAk, O.
dc.contributor.authorGulsun, S.
dc.contributor.authorTekin, R.
dc.contributor.authorUlug, M.
dc.contributor.authorDuygu, F.
dc.date.accessioned2024-04-24T17:11:23Z
dc.date.available2024-04-24T17:11:23Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractThis study reviewed the clinical, laboratory, therapeutic and prognostic data on genitourinary involvement of brucellosis in this largest case series reported. This multicentre study pooled adult patients with genitourinary brucellar involvement from 34 centres treated between 2000 and 2013. Diagnosis of the disease was established by conventional methods. Overall 390 patients with genitourinary brucellosis (352 male, 90.2%) were pooled. In male patients, the most frequent involved site was the scrotal area (n=327, 83.8%), as epididymo-orchitis (n=204, 58%), orchitis (n=112, 31.8%) and epididymitis (n=11, 3.1%). In female patients, pyelonephritis (n=33/38, 86.8%) was significantly higher than in male patients (n=11/352, 3.1%; p<0.0001). The mean blood leukocyte count was 7530 +/- 3115/mm(3). Routine laboratory analysis revealed mild to moderate increases for erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP). The mean treatment duration and length of hospital stay were significantly higher when there were additional brucellar foci (p<0.05). Surgical operations including orchiectomy and abscess drainage were performed in nine (2.3%) patients. Therapeutic failure was detected in six (1.5%), relapse occurred in four (1%), and persistent infertility related to brucellosis occurred in one patient. A localized scrotal infection in men or pyelonephritis in women in the absence of leucocytosis and with mild to moderate increases in inflammatory markers should signal the possibility of brucellar genitourinary disease.en_US
dc.identifier.doi10.1111/1469-0691.12680
dc.identifier.endpageO853en_US
dc.identifier.issn1198-743X
dc.identifier.issn1469-0691
dc.identifier.issue11en_US
dc.identifier.pmid24831227
dc.identifier.scopus2-s2.0-84917674224
dc.identifier.scopusqualityQ1
dc.identifier.startpageO847en_US
dc.identifier.urihttps://doi.org/10.1111/1469-0691.12680
dc.identifier.urihttps://hdl.handle.net/11468/17469
dc.identifier.volume20en_US
dc.identifier.wosWOS:000346337000011
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherElsevier Sci Ltden_US
dc.relation.ispartofClinical Microbiology and Infection
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBrucellaeen_US
dc.subjectBrucellosisen_US
dc.subjectEpididymoorchitisen_US
dc.subjectGenitourinaryen_US
dc.subjectOrchitisen_US
dc.titleGenitourinary brucellosis: results of a multicentric studyen_US
dc.titleGenitourinary brucellosis: results of a multicentric study
dc.typeArticleen_US

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