Evaluation of celiac disease with uniphasic and multiphasic dynamic MDCT imaging

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dc.authorid0000-0002-3784-7622en_US
dc.contributor.authorGöya, Cemil
dc.contributor.authorDündar, İlyas
dc.contributor.authorÖzgökçe, Mesut
dc.contributor.authorTürkoğlu, Saim
dc.contributor.authorTürko, Ensar
dc.contributor.authorÖzkaçmaz, Sercan
dc.contributor.authorAydoğdu, Gülay
dc.contributor.authorAlmalı, Necat
dc.date.accessioned2022-12-13T12:22:29Z
dc.date.available2022-12-13T12:22:29Z
dc.date.issued2021en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Tıbbi Patoloji Ana Bilim Dalıen_US
dc.description.abstractPurpose An analysis of dynamic contrast MRI has been shown to provide valuable information about disease activity in Crohn's disease and Celiac disease (CD). However, there are no reports of dynamic multi-detector computer tomography use in patients with CD. The aim of this study is to determine and compare the perfusion dynamics of the patients treated with control subjects and the perfusion dynamics in patients with untreated CD, using dynamic contrast in MDCT and compare studying contrast dynamics in Marsh types as well. Methods In this retrospective study, uniphasic and multiphasic MDCT, untreated, treated, incompatible CD patients and healthy control group duodenum wall thickness and HU values were compared in terms of patient groups and modified Marsh types. Result In dynamic CT, the highest contrast curve was observed in the untreated group and Marsh type 1. While the contrast curve of the untreated and non-compliant patients increased rapidly and showed wash out, the type 4 contrast curve was observed, whereas the treated and control group slowly increased type 5 contrast curve. In the contrast-enhanced CT in the venous phase, in the ROC analysis between Marsh 1-2 and Marsh 3a-c, the sensitivity was 97% and the specificity was 87% when the cut off was taken as 4.45 mm for wall thickness (p: 0.005). Conclusion Contrast-enhanced single-phase and dynamic MDCT imaging in CD patients may be useful in evaluating the inflammatory and pathological process in the small intestine.en_US
dc.identifier.citationGöya, C., Dündar, İ., Özgökçe, M., Türkoğlu, S., Türko, E., Özkaçmaz, S. ve diğerleri. (2021). Necat Evaluation of celiac disease with uniphasic and multiphasic dynamic MDCT imaging. Abdominal Radiology, 46(12), 5564-5573.en_US
dc.identifier.doi10.1007/s00261-021-03253-y
dc.identifier.endpage5573en_US
dc.identifier.issn2366-004X
dc.identifier.issn2366-0058
dc.identifier.issue12en_US
dc.identifier.pmid34415409
dc.identifier.scopus2-s2.0-85113176069
dc.identifier.scopusqualityQ1
dc.identifier.startpage5564en_US
dc.identifier.urihttps://link.springer.com/article/10.1007/s00261-021-03253-y
dc.identifier.urihttps://hdl.handle.net/11468/11040
dc.identifier.volume46en_US
dc.identifier.wosWOS:000686875300004
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorAydoğdu, Gülay
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofAbdominal Radiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCeliac diseaseen_US
dc.subjectMulti-detector computer tomographyen_US
dc.subjectMarsh typesen_US
dc.subjectDuodenum wallen_US
dc.subjectHounsfield uniten_US
dc.titleEvaluation of celiac disease with uniphasic and multiphasic dynamic MDCT imagingen_US
dc.titleEvaluation of celiac disease with uniphasic and multiphasic dynamic MDCT imaging
dc.typeArticleen_US

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