Comparison of OCT findings of schizophrenia patients using FGA, Clozapine, and SGA other than Clozapine

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dc.authorid0000-0002-6008-378Xen_US
dc.contributor.authorOrum, Mehmet Hamdi
dc.contributor.authorBulut, Mahmut
dc.contributor.authorKaradağ, Ayşe Sevgi
dc.contributor.authorDumlupınar, Ebru
dc.contributor.authorKalenderoğlu, Aysun
dc.date.accessioned2021-06-04T12:21:59Z
dc.date.available2021-06-04T12:21:59Z
dc.date.issued2020en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Ruh Sağlığı ve Hastalıkları Ana Bilim Dalıen_US
dc.descriptionWOS:000647554000001
dc.description.abstractObjective: The effect of antipsychotic (AP) drugs on optical coherence tomography (OCT) findings in schizophrenia has not yet been fully elucidated. In this study, we aimed to investigate the effects of APs (the first generation antipsychotic group [FGAG], the second generation antipsychotic group [SGAG], the clozapine group [CG]) on OCT findings in schizophrenia. Methods: The thickness of the retinal nerve fiber layer (RNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), and choroidal thickness were measured using a spectral OCT device. Results: No significant difference was found between FGAG, SGAG, CG (p > 0.05) while there was a significant difference between the control group and the patients group in terms of RNFL, GCL, and IPL (p < 0.05). A significant difference between SGAG and CG, FGAG (p < 0.05); between control group and FGAG (p < 0.05) were found in terms of choroidal thickness. Conclusion: These findings suggested the deterioration of the metabolic parameters due to the SGA use. Thinner choroidal layer thickness in the CG compared to the SGAG and control group was thought to be related to the patients using clozapine had a resistance to the treatmenten_US
dc.identifier.citationOrum, M.H., Bulut, M., Karadağ, A.S., Dumlupınar, E. ve Kalenderoğlu, A. (2020). Comparison of OCT findings of schizophrenia patients using FGA, Clozapine, and SGA other than Clozapine. Archives of Clinical Psychiatry, 47(6), 165-175.en_US
dc.identifier.doi10.15761/0101-60830000000257
dc.identifier.endpage175en_US
dc.identifier.issn0101-6083
dc.identifier.issn1806-938X
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-85105305406
dc.identifier.scopusqualityQ4
dc.identifier.startpage165en_US
dc.identifier.urihttps://www.archivespsy.com/wp-content/uploads/2020/12/RPC-2019-0181.pdf
dc.identifier.urihttps://hdl.handle.net/11468/7025
dc.identifier.volume47en_US
dc.identifier.wosWOS:000647554000001
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorBulut, Mahmut
dc.language.isoenen_US
dc.publisherUniv Sao Paulo, Ins Psiquiatriaen_US
dc.relation.ispartofArchives of Clinical Psychiatry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntipsychoticsen_US
dc.subjectRetinal ganglion cellen_US
dc.subjectChoroiden_US
dc.subjectOptical coherence tomographyen_US
dc.subjectSchizophreniaen_US
dc.titleComparison of OCT findings of schizophrenia patients using FGA, Clozapine, and SGA other than Clozapineen_US
dc.titleComparison of OCT findings of schizophrenia patients using FGA, Clozapine, and SGA other than Clozapine
dc.typeArticleen_US

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