Assessment of Long-Term Outcomes in Hbs Ag-Negative Renal Transplant Recipients Transplanted from Hbs Ag-Positive Donors

dc.contributor.authorYilmaz, Vural Taner
dc.contributor.authorUlger, Burak Veli
dc.contributor.authorAliosmanoglu, Ibrahim
dc.contributor.authorErbis, Halil
dc.contributor.authorTuna, Yasar
dc.contributor.authorAkbas, Halide
dc.contributor.authorOzdem, Sebahat
dc.date.accessioned2024-04-24T17:33:15Z
dc.date.available2024-04-24T17:33:15Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: The aim of this study was to evaluate the long-term outcomes of renal transplantation from Hbs Ag-positive donors to Hbs Ag-negative recipients. Material/Methods: A total of 78 patients who underwent renal transplantation in our clinic between January 2006 and May 2014 were included in the study. Patients were divided into 2 groups: Group 1: Donor Hbs Ag (+) (n=26, Hbs Ab (-), Hbe Ag (-), Hbe Ab (+), Hbc Ig total (+) and HBV DNA (+), male/female (M/F): 16 (61.5%)/10 (38.5%), and Group 2: Donor Hbs Ag (-) (n=52, M/F: 41 (78.8%)/11 (21.2%). Hbs Ab levels were similar in recipients in both groups. Data were collected retrospectively. Analyses were performed by using SPSS 20.0 software, and patient and graft survival were measured by using Kaplan-Meier survival curve and compared by using the log-rank test. Results: Demographic data were similar in the 2 groups. The rate of acute Hepatitis B infection was significantly higher in Group 1 than in Group 2 [n=3 (11.5%) vs. n=0 (0%), respectively, p=0.012]. Acute hepatitis B attacks were detected in vaccinated patients. Graft survival rates (groups 1 and 2, respectively; at 1st, 3rd, 5th and 8th years: 95% vs. 96%, 95% vs. 94%, 85% vs. 88%, 85% vs. 82%, p=0.970) and patient survival rates (p=0.098), acute rejection rates (p=0.725), delayed graft function, chronic allograft dysfunction, new-onset diabetes after transplantation (NODAT), cytomegalovirus infection, and the need for postoperative dialysis and plasmapheresis were similar between groups. Conclusions: Our study revealed that the risk of developing acute hepatitis B was higher in patients renally transplanted from Hbs Ag (+) donors, but the other clinical outcomes were similar between groups.en_US
dc.identifier.endpage396en_US
dc.identifier.issn1425-9524
dc.identifier.pmid26156252
dc.identifier.scopus2-s2.0-84938253303
dc.identifier.scopusqualityQ2
dc.identifier.startpage390en_US
dc.identifier.urihttps://hdl.handle.net/11468/20568
dc.identifier.volume20en_US
dc.identifier.wosWOS:000357644800001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherInt Scientific Information, Incen_US
dc.relation.ispartofAnnals of Transplantation
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHepatitis Ben_US
dc.subjectKidney Transplantationen_US
dc.subjectTissue Donorsen_US
dc.titleAssessment of Long-Term Outcomes in Hbs Ag-Negative Renal Transplant Recipients Transplanted from Hbs Ag-Positive Donorsen_US
dc.titleAssessment of Long-Term Outcomes in Hbs Ag-Negative Renal Transplant Recipients Transplanted from Hbs Ag-Positive Donors
dc.typeArticleen_US

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