Prognostic value of Golgi P 73 and Beta 2-microglobulin in patients with Viral Hepatitis B

Basit Öğe Kaydı
dc.authorid0000-0003-4577-4475en_US
dc.contributor.authorÖzcan, Deveci
dc.contributor.authorKaplan, İbrahim
dc.contributor.authorTekİn, Recep
dc.contributor.authorÇelen, Mustafa Kemal
dc.contributor.authorBozkurt, Fatma
dc.contributor.authorAslan, Emel
dc.contributor.authorCerrah, Serkan
dc.date.accessioned2021-09-02T07:59:43Z
dc.date.available2021-09-02T07:59:43Z
dc.date.issued2020en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Ana Bilim Dalıen_US
dc.description.abstractPrevious studies detected higher Golgi protein 73 levels in the serum of patients with chronic liver disease. The Beta-2 microglobulin levels were also observed to be higher in patients with chronic hepatitis B infection compared to the inactive carriers and the protein plays an important role in the response to viral infections. The aim of the present study was to assess the liver fibrosis through non-invasive methods in chronic hepatitis B patients. Three groups were included in the study. The first group comprised of the patients who were admitted to the Infectious Diseases and Clinical Microbiology clinic to undergo a liver biopsy, while the second group included the patients who were admitted inactive hepatitis B carriers. The third group comprised the healthy controls. The Golgi p-73 and Beta-2 microglobulin levels in the plasma were determined using the ELISA method. Beta-2 microglobulin level was highest in the patients group and the difference was statistically significant. No significant difference was observed between the carriers group and the group of healthy controls. The Golgi P-73 values were significantly higher in the patients group in comparison to both other groups. However, the mean Golgi p-73 value was also significantly higher in the carrier group compared to the control group. In patients who are followed up with the diagnosis of chronic hepatitis B and who have undergone biopsies as candidates for treatment, the Beta-2 microglobulin and Golgi p-73 values may be important markers since they indicate the extent of the liver damage.en_US
dc.identifier.citationÖzcan, D., Kaplan, İ., Tekin, R., Çelen, M. K., Bozkurt, F. ve Aslan, E. ve diğerleri (2020). Prognostic value of Golgi P 73 and Beta 2-microglobulin in patients with Viral Hepatitis B. Acta Biochimica Polonica, 67(!), 131-134.en_US
dc.identifier.doi10.18388/ABP.2020_5209
dc.identifier.endpage134en_US
dc.identifier.issn0001-527X
dc.identifier.issue1en_US
dc.identifier.pmid32191420
dc.identifier.scopus2-s2.0-85082342206
dc.identifier.scopusqualityQ3
dc.identifier.startpage131en_US
dc.identifier.urihttps://ojs.ptbioch.edu.pl/index.php/abp/article/view/5209
dc.identifier.urihttps://hdl.handle.net/11468/7411
dc.identifier.volume67en_US
dc.identifier.wosWOS:000520883500017
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKaplan, İbrahim
dc.institutionauthorTekİn, Recep
dc.institutionauthorÇelen, Mustafa Kemal
dc.institutionauthorBozkurt, Fatma
dc.institutionauthorDayan, Saim
dc.language.isoenen_US
dc.publisherActa Biochimica Polonicaen_US
dc.relation.ispartofActa Biochimica Polonica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBeta-2 microglobulinen_US
dc.subjectGolgi protein-73en_US
dc.subjectHepatitis Ben_US
dc.subjectPrognosisen_US
dc.titlePrognostic value of Golgi P 73 and Beta 2-microglobulin in patients with Viral Hepatitis Ben_US
dc.titlePrognostic value of Golgi P 73 and Beta 2-microglobulin in patients with Viral Hepatitis B
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Prognostic value of Golgi P 73 and Beta 2-microglobulin in.pdf
Boyut:
251.68 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale Dosyası
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Dahili Tıp Bilimleri Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu