Clinical presentation and management of fasciola hepatica infection: Single-center experience

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dc.contributor.authorKaya, Muhsin
dc.contributor.authorBeştaş, Remzi
dc.contributor.authorÇetin, Sedat
dc.date.accessioned2024-04-05T13:25:41Z
dc.date.available2024-04-05T13:25:41Z
dc.date.issued2011en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıklar Ana Bilim Dalıen_US
dc.description.abstractAIM: To identify the characteristic clinical, laboratory and radiological findings and response to treatment in patients with fascioliasis. METHODS: Patients who were diagnosed with Fasciola hepatica infection were included in this prospective study. Initial clinical, laboratory and radiological findings were recorded. All patients were followed until a complete response was achieved or for 6 mo after treatment discontinuation. RESULTS: Fasciola hepatica infection was diagnosed in 30 patients (24 females; mean age: 42.6 years) between January 2008 and February 2011. Twenty-two (73%) patients had hepatic phase fascioliasis, 5 patients had biliary phase, and 3 patients had biliary phase associated with acute pancreatitis. Of the 8 patients with biliary phase fascioliasis, 2 patients displayed features that overlapped with both hepatic and biliary phase. Abdominal pain and right upper abdominal tenderness were the most prominent signs and symptoms in all patients. Eosinophilia was the most prominent laboratory abnormality in both patients with hepatic and biliary phase (100% and 50%, respectively respectively). Multiple nodular lesions like micro-abscesses on abdominal computerized tomography were the main radiological findings in patients with hepatic phase. Small linear filling defects in the distal choledochus were the main endoscopic retrograde cholangiopancreatography (ERCP) findings in patients with biliary phase. Patients with hepatic phase were treated with triclabendazole alone, and patients with biliary phase were treated with triclabendazole and had live Fasciola hepatica extracted from the bile ducts during ERCP. CONCLUSION: Fasciola hepatica infection should be considered in the differential diagnosis of patients with hepatic or biliary disease and/or acute pancreatitis associated with eosinophilia.en_US
dc.identifier.citationKaya, M., Beştaş, R. ve Çetin, S. (2011). Clinical presentation and management of fasciola hepatica infection: Single-center experience. World Journal of Gastroenterology, 17(44), 4899-4904.en_US
dc.identifier.doi10.3748/wjg.v17.i44.4899
dc.identifier.endpage4904en_US
dc.identifier.issn1007-9327
dc.identifier.issue44en_US
dc.identifier.pmid22171131
dc.identifier.scopus2-s2.0-83155177154
dc.identifier.scopusqualityQ1
dc.identifier.startpage4899en_US
dc.identifier.urihttps://www.wjgnet.com/1007-9327/full/v17/i44/4899.htm
dc.identifier.urihttps://hdl.handle.net/11468/13865
dc.identifier.volume17en_US
dc.identifier.wosWOS:000298168800009
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKaya, Muhsin
dc.institutionauthorBeştaş, Remzi
dc.institutionauthorÇetin, Sedat
dc.language.isoenen_US
dc.publisherBaishideng Publishing Groupen_US
dc.relation.ispartofWorld Journal of Gastroenterology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCholangitisen_US
dc.subjectFasciola hepaticaen_US
dc.subjectLiver abscessesen_US
dc.subjectPancreatitisen_US
dc.subjectTriclabendazoleen_US
dc.titleClinical presentation and management of fasciola hepatica infection: Single-center experienceen_US
dc.titleClinical presentation and management of fasciola hepatica infection: Single-center experience
dc.typeArticleen_US

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