Evaluation of Anthropometric and Metabolic Parameters in Obstructive Sleep Apnea

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dc.contributor.authorYildirim, Yasar
dc.contributor.authorYilmaz, Sureyya
dc.contributor.authorGuven, Mehmet
dc.contributor.authorKilinc, Faruk
dc.contributor.authorKara, Ali Veysel
dc.contributor.authorYilmaz, Zulfukar
dc.contributor.authorKirbas, Gokhan
dc.date.accessioned2024-04-24T17:12:14Z
dc.date.available2024-04-24T17:12:14Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractAims. Sleep disorders have recently become a significant public health problem worldwide and have deleterious health consequences. Obstructive sleep apnea (OSA) is the most common type of sleep-related breathing disorders. We aimed to evaluate anthropometric measurements, glucose metabolism, and cortisol levels in patients with obstructive sleep apnea (OSA). Materials and Methods. A total of 50 patients with a body mass index >= 30 and major OSA symptoms were included in this study. Anthropometric measurements of the patients were recorded and blood samples were drawn for laboratory analysis. A 24-hour urine sample was also collected from each subject for measurement of 24-hour cortisol excretion. Patients were divided equally into 2 groups according to polysomnography results: control group with an apnea-hypopnea index (AHI) <5 (n = 25) and OSA group with an AHI = 5 (n = 25). Results. Neck and waist circumference, fasting plasma glucose, HbA1c, late-night serum cortisol, morning serum cortisol after 1 mg dexamethasone suppression test, and 24-hour urinary cortisol levels were significantly higher in OSA patients compared to control subjects. Newly diagnosed DM was more frequent in patients with OSA than control subjects (32% versus 8%, p = 0.034). There was a significant positive correlation between AHI and neck circumference, glucose, and latenight serum cortisol. Conclusions. Our study indicates that increased waist and neck circumferences constitute a risk for OSA regardless of obesity status. In addition, OSA has adverse effects on endocrine function and glucose metabolism.en_US
dc.identifier.doi10.1155/2015/189761
dc.identifier.issn2090-1836
dc.identifier.issn2090-1844
dc.identifier.pmid26257957
dc.identifier.scopus2-s2.0-84938264232
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1155/2015/189761
dc.identifier.urihttps://hdl.handle.net/11468/17900
dc.identifier.volume2015en_US
dc.identifier.wosWOS:000216517200002
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherHindawi Ltden_US
dc.relation.ispartofPulmonary Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subject[No Keyword]en_US
dc.titleEvaluation of Anthropometric and Metabolic Parameters in Obstructive Sleep Apneaen_US
dc.titleEvaluation of Anthropometric and Metabolic Parameters in Obstructive Sleep Apnea
dc.typeArticleen_US

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