Neutrophil–lymphocyte ratio as a prognostic factor in laryngeal carcinoma

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dc.authorid0000-0003-4551-8439en_US
dc.contributor.authorYılmaz, Beyhan
dc.contributor.authorŞengül, Engin
dc.contributor.authorGül, Aylin
dc.contributor.authorAlabalık, Ulaş
dc.contributor.authorÖzkurt, Fazıl Emre
dc.contributor.authorAkdağ, Mehmet
dc.contributor.authorTopçu, İsmail
dc.date.accessioned2024-01-02T06:51:40Z
dc.date.available2024-01-02T06:51:40Z
dc.date.issued2018en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kulak Burun ve Boğaz Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractAim of this study; investigate whether neutro-phils/lymphocyte ratio (NLR) could be used as a prognostic factor in larynx cancer. The correlation between preoperative peripheral blood NLR and age, gender, smoking, alcohol use, clinical stage and differentiation degree was examined. One hundered fourty-four patients in Dicle University Department of Otorhinolaryngology between the years of 2005 and 2014 were included in the study. Clinical and preoperative laboratory data of patients were screened retrospectively from archive files of otorhinolaryngology and the pathology results were screened retrospectively from archive files of pathology. The study was approved by the local ethics committee of the department and carried out in accordance with the declaration of Helsinki as amended in 2013. Statistical analyses were performed using the SPSS 15.0 software package for Windows (SPSS inc., Chicago, IL, USA). There was a significant difference between NLR and clinical stage (p = 0.003) smoking (p = 0,001) and alcohol use (p = 0.001). When NLR was analyzed in detail according to the degree of tumor differentiation; significant differences were observed between G1 and G2 (p = 0.007) and between G1 and G3 (p = 0.001). Light of these findings, NLR is a cheap and easily accessible marker which can be used as a prognostic faxtor in laryngeal cancer. It is thougkt to shed light on the studies which will be conducted with more patients.en_US
dc.identifier.citationYılmaz, B., Şengül, E., Gül, A., Alabalık, U., Özkurt, F. E., Akdağ, M. ve diğerleri. (2018). Neutrophil–lymphocyte ratio as a prognostic factor in laryngeal carcinoma. Indian Journal of Otolaryngology and Head and Neck Surgery, 70(2), 175-179.en_US
dc.identifier.doi10.1007/s12070-014-0769-4en_US
dc.identifier.endpage179en_US
dc.identifier.issn2231-3796
dc.identifier.issue2en_US
dc.identifier.pmid29977836en_US
dc.identifier.scopus2-s2.0-85053668556en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage175en_US
dc.identifier.urihttps://link.springer.com/article/10.1007/s12070-014-0769-4
dc.identifier.urihttps://hdl.handle.net/11468/13123
dc.identifier.volume70en_US
dc.identifier.wosWOS:000436119700001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorYılmaz, Beyhan
dc.institutionauthorŞengül, Engin
dc.institutionauthorGül, Aylin
dc.institutionauthorAlabalık, Ulaş
dc.institutionauthorÖzkurt, Fazıl Emre
dc.institutionauthorAkdağ, Mehmet
dc.institutionauthorTopçu, İsmail
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofIndian Journal of Otolaryngology and Head and Neck Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectLaryngeal canceren_US
dc.subjectNeutrophils lymphocyte ratioen_US
dc.subjectPrognostic factoren_US
dc.titleNeutrophil–lymphocyte ratio as a prognostic factor in laryngeal carcinomaen_US
dc.typeArticleen_US

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