Biological and chemical comparison of natural and cultivated samples of satureja macrantha C.A.Mey

dc.authorid0000-0002-0988-9462en_US
dc.authorid0000-0002-2193-8386en_US
dc.authorid0000-0001-6160-5626en_US
dc.authorid0000-0002-4090-7227en_US
dc.contributor.authorAkdeniz, Mehmet
dc.contributor.authorYener, İsmail
dc.contributor.authorErtaş, Abdulselam
dc.contributor.authorFırat, Mehmet
dc.contributor.authorReşitoğlu, Barış
dc.contributor.authorHaşimi, Nesrin
dc.contributor.authorKandemir, Sevgi İrtegün
dc.contributor.authorYılmaz, Mustafa Abdullah
dc.contributor.authorDemirköz, Aslı Barla
dc.contributor.authorKolak, Ufuk
dc.contributor.authorÖksuz, Sevil
dc.date.accessioned2021-07-01T13:00:30Z
dc.date.available2021-07-01T13:00:30Z
dc.date.issued2021en_US
dc.departmentDicle Üniversitesi, Eczacılık Fakültesi, Eczacılık Meslek Bililmleri Bölümüen_US
dc.descriptionWOS:000658306500012
dc.description.abstractAbstract: In this study, investigation on the essential oils and ethanol extracts of naturally grown and cultivated Satureja macrantha samples were reported. The essential oil, flavour and terpenoid-steroid-flavonoid contents of S. macrantha samples were determined by GC-MS and their phenolic contents by LC-MS/MS. Besides, the biological activities of the samples were investigated for their antioxidant, anti-Alzheimer, antimicrobial, cytotoxic, antityrosinase, antiurease, antielastase and anticollagenase properties. The phenolic content and antioxidant capacity of the cultivated sample were higher than those of the naturally grown sample. According to the GC-MS results, terpinene-4-ol (30.9%) and p-cymene (56.7%) were determined as the major components in the essential oils of the naturally grown and cultivated S. macrantha, respectively. The flavour analysis results showed that cis-sabinene hydrate (20.7%) and carvacrol (42.2%) were found to be the major components in the naturally grown and cultivated samples, respectively. While the naturally grown sample was rich in abietane diterpenoids (ferruginol (17.5 mg analyte/g extract) and sugiol (4.2 mg analyte/g extract)), these components were not detected in the cultivated sample. The rosmarinic acid content (0.20 and 24.87 mg analyte/g extract, respectively) of the cultivated sample was found to be significantly higher than that of the natural sample. The biological activities of the samples were determined to be changed in parallel with their chemical contents that are due to factors such as climatic conditions, and soil structure.en_US
dc.identifier.citationAkdeniz, M, Yener, İ., Ertaş, A., Fırat, M., Reşitoğlu, B., Haşimi, N. ve diğerleri. (2021). Biological and chemical comparison of natural and cultivated samples of satureja macrantha C.A.Mey. Records of Natural Products, 15(6), 568-584.en_US
dc.identifier.doi10.25135/rnp.237.21.02.1957
dc.identifier.endpage584en_US
dc.identifier.issn1307-6167
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-85108657684
dc.identifier.scopusqualityQ2
dc.identifier.startpage568en_US
dc.identifier.trdizinidTRDizinIdYok
dc.identifier.urihttps://www.acgpubs.org/doc/20210529145924A11-237-RNP-2102-1957.pdf
dc.identifier.urihttps://hdl.handle.net/11468/7194
dc.identifier.volume15en_US
dc.identifier.wosWOS:000658306500012
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorYener, İsmail
dc.institutionauthorErtaş, Abdulselam
dc.institutionauthorKandemir, Sevgi İrtegün
dc.institutionauthorYılmaz, Mustafa Abdullah
dc.language.isoenen_US
dc.publisherACG Publicationsen_US
dc.relation.ispartofRecords of Natural Products
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSatureja macranthaen_US
dc.subjectEssential oilen_US
dc.subjectFlavouren_US
dc.subjectTerpenoid contenten_US
dc.subjectBiological activitiesen_US
dc.subjectSpectroscopic analysesen_US
dc.titleBiological and chemical comparison of natural and cultivated samples of satureja macrantha C.A.Meyen_US
dc.titleBiological and chemical comparison of natural and cultivated samples of satureja macrantha C.A.Mey
dc.typeArticleen_US

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