The antioxidant effect of Michauxia campanuloides on rat ovaries

dc.authorid0000-0002-0191-3245en_US
dc.authorid0000-0002-1693-6378en_US
dc.contributor.authorKurt, S.
dc.contributor.authorKoca, R. H.
dc.contributor.authorHürkul, M. M.
dc.contributor.authorŞeker, U.
dc.contributor.authorKöroğlu, A.
dc.date.accessioned2022-12-22T12:44:22Z
dc.date.available2022-12-22T12:44:22Z
dc.date.issued2021en_US
dc.departmentDicle Üniversitesi, Veteriner Fakültesi, Klinik Bilimler Bölümü, Doğum ve Jinekoloji Ana Bilim Dalıen_US
dc.description.abstractThis study investigated how Michauxia campanuloides affects the Proliferating Cell Nuclear Antigen (PCNA) expression in granulosa cells, the ovarian histomorphology and serum total antioxidant capacity (TAC) in rats. Rats were divided into control (C), treatment 1 (T 1) and treatment 2 (T 2) groups. The rats in the T 1 and T 2 groups received aqueous extract of M. campanuloides at doses of 20 mg/kg/day and 40 mg/kg/day orally for 21 days, respectively. Serum TAC levels, follicles counts including primordial, primary, preantral, antral and atretic follicles, and PCNA expression in granulosa cells were evaluated. Numbers of preantral follicles increased in T 1 and T 2 groups compared to C group (P < 0.05). TAC and numbers of preantral and antral follicles increased in T 2 group compared to T 1 and C groups (P < 0.05). PCNA expression in granulosa cells was increased in T 2 group compared to T 1 and C groups (P <0.01). In conclusion, treatment with M. campanuloides had positive effects on antioxidant activity, follicular dynamics, and PCNA expression of granulosa cell in rats.en_US
dc.identifier.citationKurt, S., Koca, R.H., Hürkul, M.M., Şeker, U. ve Köroğlu, A. (2021). The antioxidant effect of Michauxia campanuloides on rat ovaries. Journal of the Hellenic Veterinary Medical Society, 72(3), 3163-3170.en_US
dc.identifier.doi10.12681/jhvms.28510
dc.identifier.endpage3170en_US
dc.identifier.issn1792-2720
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-85119679016
dc.identifier.scopusqualityQ4
dc.identifier.startpage3163en_US
dc.identifier.urihttps://ejournals.epublishing.ekt.gr/index.php/jhvms/article/view/28510
dc.identifier.urihttps://hdl.handle.net/11468/11109
dc.identifier.volume72en_US
dc.identifier.wosWOS:000713498000021
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorKurt, Serdal
dc.institutionauthorŞeker, Uğur
dc.language.isoenen_US
dc.publisherHellenic Veterinary Medical Societyen_US
dc.relation.ispartofJournal of the Hellenic Veterinary Medical Society
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntioxidanten_US
dc.subjectMichauxia campanuloidesen_US
dc.subjectOvarianen_US
dc.subjectPCNAen_US
dc.subjectRaten_US
dc.titleThe antioxidant effect of Michauxia campanuloides on rat ovariesen_US
dc.titleThe antioxidant effect of Michauxia campanuloides on rat ovaries
dc.typeArticleen_US

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