The antioxidant effect of Michauxia campanuloides on rat ovaries
dc.authorid | 0000-0002-0191-3245 | en_US |
dc.authorid | 0000-0002-1693-6378 | en_US |
dc.contributor.author | Kurt, S. | |
dc.contributor.author | Koca, R. H. | |
dc.contributor.author | Hürkul, M. M. | |
dc.contributor.author | Şeker, U. | |
dc.contributor.author | Köroğlu, A. | |
dc.date.accessioned | 2022-12-22T12:44:22Z | |
dc.date.available | 2022-12-22T12:44:22Z | |
dc.date.issued | 2021 | en_US |
dc.department | Dicle Üniversitesi, Veteriner Fakültesi, Klinik Bilimler Bölümü, Doğum ve Jinekoloji Ana Bilim Dalı | en_US |
dc.description.abstract | This study investigated how Michauxia campanuloides affects the Proliferating Cell Nuclear Antigen (PCNA) expression in granulosa cells, the ovarian histomorphology and serum total antioxidant capacity (TAC) in rats. Rats were divided into control (C), treatment 1 (T 1) and treatment 2 (T 2) groups. The rats in the T 1 and T 2 groups received aqueous extract of M. campanuloides at doses of 20 mg/kg/day and 40 mg/kg/day orally for 21 days, respectively. Serum TAC levels, follicles counts including primordial, primary, preantral, antral and atretic follicles, and PCNA expression in granulosa cells were evaluated. Numbers of preantral follicles increased in T 1 and T 2 groups compared to C group (P < 0.05). TAC and numbers of preantral and antral follicles increased in T 2 group compared to T 1 and C groups (P < 0.05). PCNA expression in granulosa cells was increased in T 2 group compared to T 1 and C groups (P <0.01). In conclusion, treatment with M. campanuloides had positive effects on antioxidant activity, follicular dynamics, and PCNA expression of granulosa cell in rats. | en_US |
dc.identifier.citation | Kurt, S., Koca, R.H., Hürkul, M.M., Şeker, U. ve Köroğlu, A. (2021). The antioxidant effect of Michauxia campanuloides on rat ovaries. Journal of the Hellenic Veterinary Medical Society, 72(3), 3163-3170. | en_US |
dc.identifier.doi | 10.12681/jhvms.28510 | |
dc.identifier.endpage | 3170 | en_US |
dc.identifier.issn | 1792-2720 | |
dc.identifier.issue | 3 | en_US |
dc.identifier.scopus | 2-s2.0-85119679016 | |
dc.identifier.scopusquality | Q4 | |
dc.identifier.startpage | 3163 | en_US |
dc.identifier.uri | https://ejournals.epublishing.ekt.gr/index.php/jhvms/article/view/28510 | |
dc.identifier.uri | https://hdl.handle.net/11468/11109 | |
dc.identifier.volume | 72 | en_US |
dc.identifier.wos | WOS:000713498000021 | |
dc.identifier.wosquality | Q4 | |
dc.indekslendigikaynak | Web of Science | |
dc.indekslendigikaynak | Scopus | |
dc.institutionauthor | Kurt, Serdal | |
dc.institutionauthor | Şeker, Uğur | |
dc.language.iso | en | en_US |
dc.publisher | Hellenic Veterinary Medical Society | en_US |
dc.relation.ispartof | Journal of the Hellenic Veterinary Medical Society | |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Antioxidant | en_US |
dc.subject | Michauxia campanuloides | en_US |
dc.subject | Ovarian | en_US |
dc.subject | PCNA | en_US |
dc.subject | Rat | en_US |
dc.title | The antioxidant effect of Michauxia campanuloides on rat ovaries | en_US |
dc.title | The antioxidant effect of Michauxia campanuloides on rat ovaries | |
dc.type | Article | en_US |
Dosyalar
Orijinal paket
1 - 1 / 1
Yükleniyor...
- İsim:
- The antioxidant effect of Michauxia campanuloides on rat ovaries.pdf
- Boyut:
- 1.13 MB
- Biçim:
- Adobe Portable Document Format
- Açıklama:
- Makale Dosyası
Lisans paketi
1 - 1 / 1
[ X ]
- İsim:
- license.txt
- Boyut:
- 1.44 KB
- Biçim:
- Item-specific license agreed upon to submission
- Açıklama: