An examination on composition of spermatozoa obtained from pre-operative and post-operative varicocele patients

Basit Öğe Kaydı
dc.contributor.authorAfsin, Muhamet
dc.contributor.authorOtludil, Birgul
dc.contributor.authorDede, Onur
dc.contributor.authorAkkus, Murat
dc.date.accessioned2024-04-24T16:18:19Z
dc.date.available2024-04-24T16:18:19Z
dc.date.issued2018
dc.departmentDicle Üniversitesien_US
dc.description.abstractVaricocele is one of the main and surgically repairable causes of male infertility, which arises from dilatation and torsion of the testicular veins in the plexus pampiniformis. In this study, we examined semen samples from 40 patients diagnosed with varicocele between the ages of 15 and 30 years, according to WHO criteria (pre-operatively, and at 3, 6, and 12 months post-operatively). The mean spermatozoa concentration was found to be 45.25 +/- 34.83 million/ml pre-operatively, while the mean post-operative concentration was 48.85 +/- 35.73 million/ml at three months, 51.72 +/- 32.82 million/ml at six months, and 49.63 +/- 28.05 million/ml at 12 months (P > 0.05). The mean rate of A + B motile spermatozoa was 35.5 +/- 14.71% pre-operatively, 42.65 +/- 16.80% at three months, 43 +/- 13.52%at six months and 44 +/- 14.76 percent at 12 months post-operatively (P < 0.05). The mean Kruger morphology score was 3.15 +/- 3.0% pre-operatively, and 3.20 +/- 2.83% at three months, 2.97 +/- 2.61%at six months and 3.27 +/- 2.50%at 12 months post-operatively (P > 0.05). The nucleus, acrosomal cap, mitochondrial structure and microtubules of the tail of the spermatozoa were examined under electron microscopy. The mean DNA fragmentation index (DFI%) of the spermatozoa was 20.57 +/- 4.60% pre-operatively, and post-operatively at 17.27 +/- 3.65% at three months, 15.5 +/- 3.23% at six months and 15.3 +/- 3.63% at 12 months (P < 0.001). The findings suggest that despite the increased count and motility, as well as the improved DNA fractures observed post-operatively in the spermatozoa of varicocele patients, the morphology rates remain intact.en_US
dc.description.sponsorshipDicle University Scientific Research Projects [14FF 15]; Diyarbakir, Turkeyen_US
dc.description.sponsorshipThis work was supported by Dicle University Scientific Research Projects (grant number 14FF 15), Diyarbakir, Turkey.en_US
dc.identifier.doi10.1016/j.repbio.2018.10.005
dc.identifier.endpage367en_US
dc.identifier.issn1642-431X
dc.identifier.issue4en_US
dc.identifier.pmid30396743
dc.identifier.scopus2-s2.0-85055803159
dc.identifier.scopusqualityQ1
dc.identifier.startpage361en_US
dc.identifier.urihttps://doi.org/10.1016/j.repbio.2018.10.005
dc.identifier.urihttps://hdl.handle.net/11468/15991
dc.identifier.volume18en_US
dc.identifier.wosWOS:000467186300007
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherInst Animal Reproduction Food Researchen_US
dc.relation.ispartofReproductive Biology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDnaen_US
dc.subjectFragmentationen_US
dc.subjectMorphologyen_US
dc.subjectSpermatozoaen_US
dc.subjectUltrastructureen_US
dc.subjectVaricoceleen_US
dc.titleAn examination on composition of spermatozoa obtained from pre-operative and post-operative varicocele patientsen_US
dc.titleAn examination on composition of spermatozoa obtained from pre-operative and post-operative varicocele patients
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu