Risk factors influencing morbidity and mortality in perforated peptic ulcer disease

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dc.contributor.authorTas, Ilhan
dc.contributor.authorUlger, Burak Veli
dc.contributor.authorOnder, Akin
dc.contributor.authorKapan, Murat
dc.contributor.authorBozdag, Zubeyir
dc.date.accessioned2024-04-24T17:27:32Z
dc.date.available2024-04-24T17:27:32Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: Peptic ulcer perforation continues to be a major surgical problem. In this study, risk factors that influence morbidity and mortality in perforated peptic ulcer disease were examined. Material and Methods: Files of 148 patients who were included in the study due to peptic ulcer perforation between January 2006 and December 2010 were retrospectively analyzed. Data regarding age, gender, complaints, time elapsed between onset of symptoms and hospital admission, physical examination findings, co-morbid diseases, laboratory and imaging findings, length of hospital stay, morbidity and mortality were recorded. Results: The study group included 129 (87.2%) male and 19 (12.8%) female patients. The mean age was 51.7 +/- 20 (15-88) years. Forty five patients (30.4%) had at least one co-morbid disease. In the postoperative period, 30 patients (20.3%) had complications. The most common complication was wound infection. Mortality was observed in 27 patients (18.2%). The most common cause of mortality was sepsis. Multivariate analysis revealed age over 60 years, presence of co-morbidities and Mannheim peritonitis index as independent risk factors for morbidity. Age over 60 years, time to admission and Mannheim peritonitis index were detected as independent risk factors for mortality. Conclusion: Early diagnosis and proper treatment are important in patients presenting with peptic ulcer perforation.en_US
dc.identifier.doi10.5152/UCD.2014.2705
dc.identifier.endpage25en_US
dc.identifier.issn2564-6850
dc.identifier.issn2564-7032
dc.identifier.issue1en_US
dc.identifier.pmid25931940
dc.identifier.scopus2-s2.0-84925750462
dc.identifier.scopusqualityQ3
dc.identifier.startpage20en_US
dc.identifier.urihttps://doi.org/10.5152/UCD.2014.2705
dc.identifier.urihttps://hdl.handle.net/11468/20036
dc.identifier.volume31en_US
dc.identifier.wosWOS:000370846000005
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isotren_US
dc.publisherAvesen_US
dc.relation.ispartofTurkish Journal of Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPeptic Ulcer Perforationen_US
dc.subjectMorbidityen_US
dc.subjectMortalityen_US
dc.subjectRisk Factorsen_US
dc.subjectTime To Admissionen_US
dc.titleRisk factors influencing morbidity and mortality in perforated peptic ulcer diseaseen_US
dc.titleRisk factors influencing morbidity and mortality in perforated peptic ulcer disease
dc.typeArticleen_US

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