The role of non-invasive oscillometric method to detect aortic stiffness in patients with subclinical hypothyroidism

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dc.authoridEvsen, Ali/0000-0002-3780-7137
dc.contributor.authorEvsen, Ali
dc.contributor.authorOylumlu, Mustafa
dc.date.accessioned2025-02-22T14:08:58Z
dc.date.available2025-02-22T14:08:58Z
dc.date.issued2024
dc.departmentDicle Üniversitesien_US
dc.description.abstractIntroduction: Subclinical hypothyroidism (SCH) is a biochemical condition that is diagnosed when peripheral free thyroid hormone levels are within normal reference laboratory range but serum thyroid-stimulating hormone (TSH) levels are mildly elevated. The aim of this study was to investigate the relationship between SCH and arterial stiffness using two different non-invasive methods, including echocardiography and oscillometric arteriography. Material and Methods: The study included 33 newly diagnosed SCH patients and 34 age- and gender-matched healthy controls. Systolic and diastolic diameters and elastic parameters of the aorta were calculated by 2D Transthoracic echocardiography (TTE). Central blood pressure and aortic stiffness values of patient groups were measured noninvasively from the brachial artery using Mobil-O-Graph arteriography. Pulse wave velocity (PWV) and augmentation index (AIx) were used as arterial stiffness indicators. Results: There was no significant difference between SCH and control groups with regard to age, gender, and body mass index (BMI). Aortic strain and aortic distensibility, were significantly lower in the SCH group than in the control group (p < 0.001). PWV and AIx which measured by Mobil-O-Graph arteriography were found to be significantly higher in the subclinical hypothyroid group compared to the control group (p < 0.05). Conclusion: Aortic stiffness assessed by TTE and Mobil-O-Graph arteriography deteriorated in patients with SCH after excluding other cardiovascular risk factors. The assessment of aortic stiffness by the oscillometric method was easy and useful for widespread clinical use.en_US
dc.identifier.doi10.1080/00015385.2024.2375486
dc.identifier.endpage1010en_US
dc.identifier.issn0001-5385
dc.identifier.issn1784-973X
dc.identifier.issue9en_US
dc.identifier.pmid38973345en_US
dc.identifier.scopus2-s2.0-85197733082en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1004en_US
dc.identifier.urihttps://doi.org/10.1080/00015385.2024.2375486
dc.identifier.urihttps://hdl.handle.net/11468/29735
dc.identifier.volume79en_US
dc.identifier.wosWOS:001265450000001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofActa Cardiologicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKA_WOS_20250222
dc.subjectArterial stiffnessen_US
dc.subjectpulse wave velocityen_US
dc.subjectaugmentation indexen_US
dc.subjectaortic strainen_US
dc.subjectaortic distensibilityen_US
dc.subjectsubclinical hypothyroidismen_US
dc.titleThe role of non-invasive oscillometric method to detect aortic stiffness in patients with subclinical hypothyroidismen_US
dc.typeArticleen_US

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