Cytopenia in adult brucellosis patients

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dc.contributor.authorKaya, Safak
dc.contributor.authorElaldi, Nazif
dc.contributor.authorDeveci, Ozcan
dc.contributor.authorEskazan, Ahmet Emre
dc.contributor.authorBekcibasi, Muhammed
dc.contributor.authorHosoglu, Salih
dc.date.accessioned2024-04-24T17:24:15Z
dc.date.available2024-04-24T17:24:15Z
dc.date.issued2018
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground & objectives: Brucellosis can lead to haematological abnormalities including cytopenia confusing with haematological malignancies. The aim of this study was to compare the main characteristics of brucellosis patients without cytopenia (Group 1) and with cytopenia (Group 2). Methods: This five-year period study which was performed in two referral hospitals in Turkey, included all adult brucellosis patients. Abnormally, low counts of leucocyte or haemoglobin or platelets in a patient were considered as cytopenia. The demographics, clinical, laboratory, treatment and outcome data were analyzed. Results: A total of 484 brucellosis patients were enrolled. Among the cases, 162 (33.5%) of them had cytopenia. One hundred and four (21.5%) had anaemia, 88 (18.8%) had thrombocytopenia, 71 (14.6%) had leucopenia and 28 (5.8%) had pancytopenia. The mean age of group 2 was 35.01 +/- 16.05 yr and it was 33.31 +/- 14.39 yr in group 1. While there was no difference between the groups in terms of duration of treatment, the median length of hospital stay (LOS) was significantly longer in group 2 (9 vs 10 days; P<0.001). The most frequently applied combination therapy consisted of doxycycline plus rifampicin and doxycycline plus streptomycin regimens. No significant difference was observed in terms of duration of treatment, LOS and restoration time of cytopenia between the patients who received either of these combinations. Interpretation & conclusions: Our findings suggested that the patients with cytopenia should be investigated for brucellosis, especially if living in, or with a history of travel to, endemic areas, in view of the increase in world travel.en_US
dc.identifier.doi10.4103/ijmr.IJMR_542_15
dc.identifier.endpage80en_US
dc.identifier.issn0971-5916
dc.identifier.pmid29749364
dc.identifier.scopus2-s2.0-85046753695
dc.identifier.scopusqualityQ1
dc.identifier.startpage73en_US
dc.identifier.urihttps://doi.org/10.4103/ijmr.IJMR_542_15
dc.identifier.urihttps://hdl.handle.net/11468/19554
dc.identifier.volume147en_US
dc.identifier.wosWOS:000432019200013
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherMedknow Publications & Media Pvt Ltden_US
dc.relation.ispartofIndian Journal of Medical Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnaemiaen_US
dc.subjectBrucellosisen_US
dc.subjectLeucopeniaen_US
dc.subjectPancytopeniaen_US
dc.subjectThrombocytopeniaen_US
dc.titleCytopenia in adult brucellosis patientsen_US
dc.titleCytopenia in adult brucellosis patients
dc.typeArticleen_US

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