The prognostic value of HALP score and sPESI in predicting in-hospital mortality in patients with pulmonary thromboembolism

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dc.authoridBelek, Sema/0000-0002-4681-8989
dc.authoridYAMAN, MAHMUT/0000-0002-0783-1419
dc.contributor.authorYaman, Mahmut
dc.contributor.authorOrak, Murat
dc.contributor.authorDurgun, Hasan Mansur
dc.contributor.authorTekin, Veysi
dc.contributor.authorUlgut, Silan Goger
dc.contributor.authorBelek, Sema
dc.contributor.authorGunel, Bercem Tugay
dc.date.accessioned2025-02-22T14:08:54Z
dc.date.available2025-02-22T14:08:54Z
dc.date.issued2024
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground Pulmonary thromboembolism (PTE), often arising from deep vein thrombosis, remains a high-mortality condition despite diagnostic advancements. Prognostic models like Pulmonary Embolism Severity Index (PESI) and sPESI identify low-risk groups effectively. The Hemoglobin, Albumin, Lymphocyte, and Platelet (HALP) score, reflecting nutritional status and systemic inflammation, shows prognostic value in cancers and cardiovascular diseases. This study examines the relationship between in-hospital mortality HALP score and simplified PESI (sPESI) in PTE patients. Methods This retrospective observational study included patients diagnosed with PTE in the emergency department of a tertiary medical faculty from 2018 to 2023. PTE diagnosis was confirmed via computed tomography pulmonary angiography. Data on transthoracic echocardiography, D-dimer levels, demographics, laboratory results, PESI, sPESI, and HALP scores, and in-hospital mortality were collected. Results In this study, clinical characteristics of 171 patients with PTE were analysed. The average age was 61.88 +/- 19.94 years, and 53.2% were female. Mortality was observed in 19.3% of patients. PESI and sPESI scores were significant predictors of mortality, with area under the curve values of 0.938 and 0.879, respectively. PESI score > 175.50 indicated a significantly higher mortality risk (HR = 18.208; P < .001), while sPESI >2.50 was also a strong predictor (HR = 11.840; P < .001). No significant cut-off value for HALP in predicting mortality was identified. Conclusions Our study supports the reliability of sPESI and PESI scores in predicting in-hospital mortality in PTE patients. However, the prognostic value of the HALP score requires further investigation. Our findings highlight the need for developing risk stratification models.en_US
dc.identifier.doi10.1093/postmj/qgae124
dc.identifier.endpage65en_US
dc.identifier.issn0032-5473
dc.identifier.issn1469-0756
dc.identifier.issue1191en_US
dc.identifier.pmid39301789en_US
dc.identifier.scopus2-s2.0-85214055835en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage60en_US
dc.identifier.urihttps://doi.org/10.1093/postmj/qgae124
dc.identifier.urihttps://hdl.handle.net/11468/29701
dc.identifier.volume101en_US
dc.identifier.wosWOS:001317007800001
dc.identifier.wosqualityQ1
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherOxford Univ Pressen_US
dc.relation.ispartofPostgraduate Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKA_WOS_20250222
dc.subjectpulmonary thromboembolismen_US
dc.subjectPESI scoreen_US
dc.subjectsPESI scoreen_US
dc.subjectHALP scoreen_US
dc.subjectmortalityen_US
dc.titleThe prognostic value of HALP score and sPESI in predicting in-hospital mortality in patients with pulmonary thromboembolismen_US
dc.typeArticleen_US

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