Importance of parathyroid hormone needle aspiration washout in adenoma localization in primary hyperparathyroidism

Basit Öğe Kaydı
dc.authorid0000-0002-5323-2257en_US
dc.contributor.authorPekkolay, Zafer
dc.contributor.authorTuzcu, Şadiye Altun
dc.date.accessioned2022-02-25T06:49:47Z
dc.date.available2022-02-25T06:49:47Z
dc.date.issued2019en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıklar Ana Bilim Dalıen_US
dc.descriptionPMD: 30834899
dc.description.abstractBACKGROUND: Primary hyperparathyroidism is an endocrine disease characterized by excessive secretion of parathyroid hormone and hypercalcemia. Although scintigraphy is commonly used for pre-operative localization, it does not always localize the parathyroid lesion. In such patients, ultrasonography can visualize the suspected lesion and needle washout sample for parathyroid hormone titer can be used to confirm parathyroid tissue. The aim of this study was to investigate the accuracy of the parathyroid hormone needle aspiration washout method in detecting the localization of parathyroid adenoma. MATERIAL AND METHODS: Patients with primary hyperparathyroidism who underwent surgery between 2010 and 2017 at the Dicle University Medical Faculty Hospital were retrospectively evaluated using medical records. Patients undergoing parathyroid hormone needle aspiration washout were performed in the suspected lesion were included in the study. Accompanied by ultrasonography, the suspected area was penetrated with needle, and negative aspiration was performed. Pre-operative scintigraphic data of patients were evaluated. Patients with positive scintigraphy, negative scintigraphy or patients who did not undergo scintigraphy were included in our study. Demographic data were presented as continuous data means ± standard deviation. Categorical variables were presented as frequency and percentage. RESULTS: Forty-nine patients (female/male, 40/9) who underwent parathyroid hormone needle aspiration washout were included in the study. Parathyroid hormone washout result was positive in 47 patients (47/49) and negative in 2 patients (2/49), sensitivity/positive predictive value (PPV) 95.91%. Twenty-six patients who had negative/suspicious scintigraphic results were diagnosed using the parathyroid hormone needle aspiration washout method (24/26, 92.3% accuracy). Parathyroid hormone needle aspiration washout without scintigraphy was performed in 13 patients (13/13, 100% accuracy). CONCLUSIONS: Parathyroid adenoma localization can be easily done using parathyroid hormone needle aspiration washout in centers experienced in adenoma localization in primary hyperparathyroidism cases in which scintigraphic results are negative or scintigraphy cannot be performed. We believe that primary parathyroid hormone needle aspiration washout can be a new localization method for adenoma localization.en_US
dc.identifier.citationPekkolay, Z. ve Tuzcu, Ş. A. (2019). Importance of parathyroid hormone needle aspiration washout in adenoma localization in primary hyperparathyroidism. Medical Science Monitor, 25, 1694-1698.en_US
dc.identifier.doi10.12659/MSM.915192
dc.identifier.endpage1698en_US
dc.identifier.issn1234-1010
dc.identifier.pmid30834899
dc.identifier.scopus2-s2.0-85062394668
dc.identifier.scopusqualityQ1
dc.identifier.startpage1694en_US
dc.identifier.urihttps://www.medscimonit.com/abstract/index/idArt/915192
dc.identifier.urihttps://hdl.handle.net/11468/9220
dc.identifier.volume25en_US
dc.identifier.wosWOS:000461189500002
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorPekkolay, Zafer
dc.language.isoenen_US
dc.publisherInternational Scientific Information, Inc.en_US
dc.relation.ispartofMedical Science Monitor
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBiopsyen_US
dc.subjectFine-Needleen_US
dc.subjectHyperparathyroidismen_US
dc.subjectPrimaryen_US
dc.subjectParathyroid Neoplasmsen_US
dc.subjectAdenomaen_US
dc.subjectAdulten_US
dc.subjectAgeden_US
dc.subject80 and overen_US
dc.subjectBiopsyen_US
dc.subjectNeedleen_US
dc.subjectFemaleen_US
dc.subjectHumansen_US
dc.subjectMaleen_US
dc.subjectMiddle Ageden_US
dc.subjectParathyroid Glandsen_US
dc.subjectParathyroid Hormoneen_US
dc.subjectRadionuclide Imagingen_US
dc.subjectRadiopharmaceuticalsen_US
dc.subjectRetrospective Studiesen_US
dc.subjectSensitivity and Specificityen_US
dc.subjectUltrasonographyen_US
dc.titleImportance of parathyroid hormone needle aspiration washout in adenoma localization in primary hyperparathyroidismen_US
dc.titleImportance of parathyroid hormone needle aspiration washout in adenoma localization in primary hyperparathyroidism
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
Importance of Parathyroid Hormone Needle.pdf
Boyut:
1014.42 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale Dosyası
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
license.txt
Boyut:
1.44 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Dahili Tıp Bilimleri Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu