Myocardial infarction and venous thrombosis in a 42-year old woman with heterozygous methylenetetrahydrofolate reductase (MTHRF) gene mutation, hyperhomocysteinemia, and protein C deficiency

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dc.contributor.authorÇakır, Ömer
dc.contributor.authorAyyıldız, Orhan
dc.contributor.authorGöz, Mustafa
dc.contributor.authorŞit, Dede
dc.contributor.authorEren, Nesimi
dc.date.accessioned2024-04-24T17:56:08Z
dc.date.available2024-04-24T17:56:08Z
dc.date.issued2007
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractObjective: Hyperhomocysteinemia and protein C deficiency have synergistic effect on the onset of thrombotic disease. Methods: We report a 42-year old woman with myocardial infarction and venous thrombosis in whom recognition of heterozygous MTHRF gene mutation, hyperhomocysteinemia, and protein C deficiency. Results: The patient was treated successfully with coronary artery bypass graft surgery and systemic anticoagulation. Conclusions: Our report emphasize that a combined hyperhomocysteinemia, and protein C deficiency may be a high risk factor for arterial and venous thromboembolic events in young adults. These patients might be candidates for indefinite anticoagulation.en_US
dc.identifier.citationÇakır, Ö., Ayyıldız, O., Göz, M., Şit, D. ve Eren, N. (2007). Myocardial infarction and venous thrombosis in a 42-year old woman with heterozygous methylenetetrahydrofolate reductase (MTHRF) gene mutation, hyperhomocysteinemia, and protein C deficiency. International Journal of Cardiology, 117(3), e98-e100.
dc.identifier.doi10.1016/j.ijcard.2006.11.204
dc.identifier.endpagee100en_US
dc.identifier.issn0167-5273
dc.identifier.issue3en_US
dc.identifier.pmid17360059en_US
dc.identifier.scopus2-s2.0-33947716365en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpagee98en_US
dc.identifier.urihttps://doi.org/10.1016/j.ijcard.2006.11.204
dc.identifier.urihttps://hdl.handle.net/11468/23313
dc.identifier.urihttps://www.sciencedirect.com/science/article/pii/S0167527307002288?via%3Dihub
dc.identifier.volume117en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.institutionauthorAyyıldız, Orhan
dc.language.isoenen_US
dc.relation.ispartofInternational Journal of Cardiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHyperhomocysteinemiaen_US
dc.subjectMthrf gene mutationen_US
dc.subjectProtein C deficiencyen_US
dc.titleMyocardial infarction and venous thrombosis in a 42-year old woman with heterozygous methylenetetrahydrofolate reductase (MTHRF) gene mutation, hyperhomocysteinemia, and protein C deficiencyen_US
dc.typeArticleen_US

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