Myocardial infarction and venous thrombosis in a 42-year old woman with heterozygous methylenetetrahydrofolate reductase (MTHRF) gene mutation, hyperhomocysteinemia, and protein C deficiency
Yükleniyor...
Tarih
2007
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: Hyperhomocysteinemia and protein C deficiency have synergistic effect on the onset of thrombotic disease. Methods: We report a 42-year old woman with myocardial infarction and venous thrombosis in whom recognition of heterozygous MTHRF gene mutation, hyperhomocysteinemia, and protein C deficiency. Results: The patient was treated successfully with coronary artery bypass graft surgery and systemic anticoagulation. Conclusions: Our report emphasize that a combined hyperhomocysteinemia, and protein C deficiency may be a high risk factor for arterial and venous thromboembolic events in young adults. These patients might be candidates for indefinite anticoagulation.
Açıklama
Anahtar Kelimeler
Hyperhomocysteinemia, Mthrf gene mutation, Protein C deficiency
Kaynak
International Journal of Cardiology
WoS Q Değeri
Scopus Q Değeri
Q1
Cilt
117
Sayı
3
Künye
Çakır, Ö., Ayyıldız, O., Göz, M., Şit, D. ve Eren, N. (2007). Myocardial infarction and venous thrombosis in a 42-year old woman with heterozygous methylenetetrahydrofolate reductase (MTHRF) gene mutation, hyperhomocysteinemia, and protein C deficiency. International Journal of Cardiology, 117(3), e98-e100.
