Synthesis of novel chiral Schiff-base ligands and their application in asymmetric nitro aldol (Henry) reaction
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Tarih
2007
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Pergamon-Elsevier Science Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Chiral Schiff-bases prepared from chiral amino alcohols catalyze the enantio selective Henry (nitro aldol) reaction between nitromethane and p-nitrobenzaldehyde in the presence of Cu(OTf)(2) and Zn(OTf)(2). Zn(OTf)(2) promoted the reaction yield, while Cu(OTf)(2) promoted the enantiomeric excess. The highest enantioselectivities were observed with ligand 3 (44% ee) and ligand 5 (47% ee). (C) 2007 Elsevier Ltd. All rights reserved.
Açıklama
Anahtar Kelimeler
[No Keyword]
Kaynak
Tetrahedron-Asymmetry
WoS Q Değeri
Q1
Scopus Q Değeri
N/A
Cilt
18
Sayı
9
