Association of Neutrophil-Lymphocyte Ratio With the Presence and Severity of Rheumatic Mitral Valve Stenosis

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dc.contributor.authorPolat, Nihat
dc.contributor.authorYildiz, Abdulkadir
dc.contributor.authorYuksel, Murat
dc.contributor.authorBilik, Mehmet Zihni
dc.contributor.authorAydin, Mesut
dc.contributor.authorAcet, Halit
dc.contributor.authorAkil, Mehmet Ata
dc.date.accessioned2024-04-24T17:14:39Z
dc.date.available2024-04-24T17:14:39Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe aim of the study is to investigate the association between the severity of rheumatic mitral valvular disease (RMVD) and the neutrophil-lymphocyte ratio (NLR). A total of 227 patients were enrolled in the study and divided into 3 groups. Patients in group 1 had rheumatic mitral stenosis (RMS), those in group 2 had RMVD without stenosis, and those in group 3 served as the control group. Group 1 was further divided into 2 groups, severe mitral stenosis (MS) and mild to moderate MS. The NLR was significantly higher in patients with severe MS when compared to those with mild to moderate MS (P = .002) while lymphocyte count was lower (P = .034). Using a cutoff level of 2.56, the NLR predicted severe RMS with a sensitivity of 75% and specificity of 74%. In conclusion, as an inexpensive, simple, and accessible marker of inflammation, the NLR may be useful in predicting the presence and severity of MS in patients with RMVD.en_US
dc.description.sponsorshipDicle University DUBAPen_US
dc.description.sponsorshipWe are grateful to Dicle University DUBAP for their sponsorship about English editing of this manuscript.en_US
dc.identifier.doi10.1177/1076029613514131
dc.identifier.endpage798en_US
dc.identifier.issn1076-0296
dc.identifier.issn1938-2723
dc.identifier.issue8en_US
dc.identifier.pmid24335245
dc.identifier.scopus2-s2.0-84921032256
dc.identifier.scopusqualityQ2
dc.identifier.startpage793en_US
dc.identifier.urihttps://doi.org/10.1177/1076029613514131
dc.identifier.urihttps://hdl.handle.net/11468/18119
dc.identifier.volume20en_US
dc.identifier.wosWOS:000343775700005
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofClinical and Applied Thrombosis-Hemostasis
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectRheumatic Valve Diseaseen_US
dc.subjectMitral Stenosisen_US
dc.subjectNeutrophil To Lymphocyte Ratioen_US
dc.subjectInflammationen_US
dc.titleAssociation of Neutrophil-Lymphocyte Ratio With the Presence and Severity of Rheumatic Mitral Valve Stenosisen_US
dc.titleAssociation of Neutrophil-Lymphocyte Ratio With the Presence and Severity of Rheumatic Mitral Valve Stenosis
dc.typeArticleen_US

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