Is a complete blood cell count useful in determining the prognosis of pulmonary embolism?

dc.contributor.authorSen, Hadice Selimoglu
dc.contributor.authorAbakay, Ozlem
dc.contributor.authorTanrikulu, Abdullah Cetin
dc.contributor.authorSezgi, Cengizhan
dc.contributor.authorTaylan, Mahsuk
dc.contributor.authorAbakay, Abdurrahman
dc.contributor.authorKaya, Halide
dc.date.accessioned2024-04-24T16:01:55Z
dc.date.available2024-04-24T16:01:55Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractPulmonary embolism (PE) is the third cardiovascular cause of hospital admission, following acute coronary syndrome and stroke. Despite high-tech diagnostic methods and new treatment modalities, PEs continue to have a high mortality rate within the first 3 months. This study was designed to assess the additional prognostic value of a complete blood cell count, renal function markers, C-reactive protein, and simplified pulmonary embolism severity index (sPESI) scoring system in PE 100-day mortality. The study retrospectively enrolled 208 consecutive patients who were hospitalized with the diagnosis of an acute PE. The patients' demographic characteristics and clinical and laboratory parameters were recorded from the hospital electronic database and patient's case notes. The primary end point of the study was an adverse 100-day outcome, defined as death from any cause. The all-cause mortality in the first 100 days was 14.42 %. The mean age was 57.87 +/- 18.17 (range: 16-93) years. We included 79 (38 %) male and 129 (62 %) female individuals. Red cell distribution width (RDW) and sPESI were found to be statistically significant predictors of PE mortality by multivariate regression analysis. On multivariate regression analysis, RDW was associated with a 4.08-fold (95 % confidence interval: 1.229-13.335, P = 0.021) increase in PE mortality. The results of this study demonstrated that RDW and sPESI may be a useful guide in predicting 100-day mortality. The elevated RDW may alert physicians to possible poor prognosis.en_US
dc.identifier.doi10.1007/s00508-014-0537-1
dc.identifier.endpage354en_US
dc.identifier.issn0043-5325
dc.identifier.issn1613-7671
dc.identifier.issue11-12en_US
dc.identifier.pmid24664312
dc.identifier.scopus2-s2.0-84903730592
dc.identifier.scopusqualityQ1
dc.identifier.startpage347en_US
dc.identifier.urihttps://doi.org/10.1007/s00508-014-0537-1
dc.identifier.urihttps://hdl.handle.net/11468/14491
dc.identifier.volume126en_US
dc.identifier.wosWOS:000338531800005
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringer Wienen_US
dc.relation.ispartofWiener Klinische Wochenschrift
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPulmonary Embolismen_US
dc.subjectPrognostic Factorsen_US
dc.subjectComplete Blood Cell Counten_US
dc.subjectRed Cell Distribution Widthen_US
dc.titleIs a complete blood cell count useful in determining the prognosis of pulmonary embolism?en_US
dc.titleIs a complete blood cell count useful in determining the prognosis of pulmonary embolism?
dc.typeArticleen_US

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