Effects of adnexal torsion on the fallopian tube in rats: A histologic and immunohistochemical study

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dc.contributor.authorTunç S.Y.
dc.contributor.authorAğaçayak E.
dc.contributor.authorYaman N.S.
dc.contributor.authorDeveci E.
dc.contributor.authorKalkanli S.
dc.contributor.authorÖzler A.
dc.date.accessioned2024-04-24T18:46:08Z
dc.date.available2024-04-24T18:46:08Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: To investigate histopathological and immunohistochemical changes in the Fallopian tube structure following ovarian torsion. Study design: Thirty fertile, female, adult Wistar albino rats, weighing 200-220 g, were randomly divided into 3 equal groups (n=10): sham, torsion, and detorsion. In the torsion and detorsion groups, bilateral adnexal torsion (3-hour ischemia) was carried out. Bilateral adnexal detorsion (3-hour reperfusion) was performed in the detorsion group. Fallopian tube sections were stained hematoxylin and eosin, periodic acid-Schiff, Mallory-Azan and immunohistochemically-stained desmin, ? smooth actin, and CD68 antibodies. Results: In the sections of the ischemic group, degeneration of epithelium, loss of cilia, dilation of blood vessels, and hemorrhages were observed. Image analysis of the studied Fallopian section revealed a significant decrease in density of desmin in the torsion group. Moreover, strong positive cytoplasmic CD68 expression was observed in the torsion group. Conclusion: The use of effective antiinflammatory treatments may contribute to the conservative surgery in preservation of ovarian reserve and tubal structure. © Science Printers and Publishers, Inc.en_US
dc.identifier.endpage289en_US
dc.identifier.issn0884-6812
dc.identifier.issue5en_US
dc.identifier.pmid25804001
dc.identifier.scopus2-s2.0-84920501839
dc.identifier.scopusqualityN/A
dc.identifier.startpage285en_US
dc.identifier.urihttps://hdl.handle.net/11468/25076
dc.identifier.volume36en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherScience Printers and Publishers Inc.en_US
dc.relation.ispartofAnalytical and Quantitative Cytology and Histology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAdnexal Torsionen_US
dc.subjectFallopian Tubeen_US
dc.subjectIschemiaen_US
dc.subjectOvarian Torsionen_US
dc.subjectReperfusionen_US
dc.subjectWistar Raten_US
dc.titleEffects of adnexal torsion on the fallopian tube in rats: A histologic and immunohistochemical studyen_US
dc.titleEffects of adnexal torsion on the fallopian tube in rats: A histologic and immunohistochemical study
dc.typeArticleen_US

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