Effects of adnexal torsion on the fallopian tube in rats: A histologic and immunohistochemical study
[ X ]
Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Science Printers and Publishers Inc.
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: To investigate histopathological and immunohistochemical changes in the Fallopian tube structure following ovarian torsion. Study design: Thirty fertile, female, adult Wistar albino rats, weighing 200-220 g, were randomly divided into 3 equal groups (n=10): sham, torsion, and detorsion. In the torsion and detorsion groups, bilateral adnexal torsion (3-hour ischemia) was carried out. Bilateral adnexal detorsion (3-hour reperfusion) was performed in the detorsion group. Fallopian tube sections were stained hematoxylin and eosin, periodic acid-Schiff, Mallory-Azan and immunohistochemically-stained desmin, ? smooth actin, and CD68 antibodies. Results: In the sections of the ischemic group, degeneration of epithelium, loss of cilia, dilation of blood vessels, and hemorrhages were observed. Image analysis of the studied Fallopian section revealed a significant decrease in density of desmin in the torsion group. Moreover, strong positive cytoplasmic CD68 expression was observed in the torsion group. Conclusion: The use of effective antiinflammatory treatments may contribute to the conservative surgery in preservation of ovarian reserve and tubal structure. © Science Printers and Publishers, Inc.
Açıklama
Anahtar Kelimeler
Adnexal Torsion, Fallopian Tube, Ischemia, Ovarian Torsion, Reperfusion, Wistar Rat
Kaynak
Analytical and Quantitative Cytology and Histology
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
36
Sayı
5
