The Relationship Between Serum Levels of Zn and Cu and Severity of Coronary Atherosclerosis

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dc.contributor.authorIslamoglu, Yahya
dc.contributor.authorEvliyaoglu, Osman
dc.contributor.authorTekbas, Ebru
dc.contributor.authorCil, Habib
dc.contributor.authorElbey, Mehmet Ali
dc.contributor.authorAtilgan, Zuhal
dc.contributor.authorKaya, Hasan
dc.date.accessioned2024-04-24T16:02:38Z
dc.date.available2024-04-24T16:02:38Z
dc.date.issued2011
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe essential trace elements play important roles in the maintainance of the normal structure and physiology of cells. Several research groups have demonstrated that they also play important roles in states of cardiovascular diseases. Our aim is to investigate whether there is a relationship between trace elements (Zn and Cu) and the degree of atherosclerosis. The sample consisted of 67 patients with coronary artery disease and 26 clinically healthy individuals. Ninety-three subjects were separated into four groups according to their Gensini scores, the number of diseased vessels, the presence of acute coronary syndrome, and ejection fraction. Each group was divided into three subgroups, and serum zinc and copper levels were measured for each individual. The serum levels of zinc and copper were found to be significantly lower in patients with atherosclerosis than in the control group, but there were no significant differences in the serum levels of Cu and Zn between severe atherosclerosis and mild atherosclerosis. In Spearman's rank correlation, the zinc and copper levels were correlated with the Gensini score and the number of diseased vessels. The present study revealed a relationship between the serum levels of zinc and copper and atherosclerosis, but not between these levels and the severity of the disease.en_US
dc.identifier.doi10.1007/s12011-011-9123-9
dc.identifier.endpage444en_US
dc.identifier.issn0163-4984
dc.identifier.issue1-3en_US
dc.identifier.pmid21720784
dc.identifier.scopus2-s2.0-84155165522
dc.identifier.scopusqualityQ1
dc.identifier.startpage436en_US
dc.identifier.urihttps://doi.org/10.1007/s12011-011-9123-9
dc.identifier.urihttps://hdl.handle.net/11468/14865
dc.identifier.volume144en_US
dc.identifier.wosWOS:000298192900041
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherHumana Press Incen_US
dc.relation.ispartofBiological Trace Element Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectTrace Elementen_US
dc.subjectZincen_US
dc.subjectCopperen_US
dc.subjectSeverity Of Atherosclerosisen_US
dc.subjectGensini Scoreen_US
dc.titleThe Relationship Between Serum Levels of Zn and Cu and Severity of Coronary Atherosclerosisen_US
dc.titleThe Relationship Between Serum Levels of Zn and Cu and Severity of Coronary Atherosclerosis
dc.typeArticleen_US

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