Intracellular Ca2+ levels in rat ventricle cells exposed to extremely low frequency magnetic field

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dc.contributor.authorSert, Cemil
dc.contributor.authorSoker, Sevda
dc.contributor.authorDeniz, Mustafa
dc.contributor.authorNergiz, Yusuf
dc.date.accessioned2024-04-24T17:20:33Z
dc.date.available2024-04-24T17:20:33Z
dc.date.issued2011
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: Electromagnetic fields can affect intracellular Ca2+ levels. The aim of this study was to determine the changes intracellular Ca2+ concentration in cardiac ventricle cells of rats exposed to 0.25 mT (2.5 Gauss) magnetic field. Methods: Forty-five male rats were introduced to this study. The rats were divided into three groups: control, sham, and experiment. The experimental group was exposed to 0.25 mT extremely low frequency (ELF) magnetic field for 14 days, 3 h/day. The sham group was treated like the experimental group, except for elf-magnetic field exposure. The control group was not subjected to anything and differed from the experimental group and sham group. In the end of experiment, rats were sacrificed, cardiac tissue was removed, and these were fixed in 10% neutral formalin. Then, ventricular cells were stained by Alizarin red staining method. Results: In the light microscopic examinations of control groups, in myofibril structures between groups, changes were not observed. In myofibril regions of the experimental group compared to other groups, increased heterogen Ca2+ accumulations were found. Conclusion: ELF magnetic fields are used in daily life. The results of this study show that intracellular Ca2+ accumulation in cardiac ventricles can increase in rats exposed to ELF magnetic field.en_US
dc.identifier.doi10.3109/15368378.2011.566773
dc.identifier.endpage20en_US
dc.identifier.issn1536-8378
dc.identifier.issn1536-8386
dc.identifier.issue1en_US
dc.identifier.pmid21554099
dc.identifier.scopus2-s2.0-79955814410
dc.identifier.scopusqualityQ2
dc.identifier.startpage14en_US
dc.identifier.urihttps://doi.org/10.3109/15368378.2011.566773
dc.identifier.urihttps://hdl.handle.net/11468/19128
dc.identifier.volume30en_US
dc.identifier.wosWOS:000290408500002
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofElectromagnetic Biology and Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMagnetic Field Exposureen_US
dc.subjectIntracellular Ca2+en_US
dc.subjectRat Ventricle Cellsen_US
dc.subjectCardiac Risken_US
dc.titleIntracellular Ca2+ levels in rat ventricle cells exposed to extremely low frequency magnetic fielden_US
dc.titleIntracellular Ca2+ levels in rat ventricle cells exposed to extremely low frequency magnetic field
dc.typeArticleen_US

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