Bioapplications of polythiophene-g-polyphenylalanine-covered surfaces

Basit Öğe Kaydı
dc.contributor.authorGüler, Emine
dc.contributor.authorAkbulut, Hüseyin
dc.contributor.authorBozokalfa, Guliz
dc.contributor.authorDemir, Bilal
dc.contributor.authorEyrilmez, Gizem Oyman
dc.contributor.authorYavuz, Murat
dc.contributor.authorDemirkol, Dilek Odacı
dc.contributor.orcid0000-0003-3452-8551
dc.contributor.orcid0000-0003-2381-9775
dc.contributor.orcid0000-0003-1642-3481
dc.date.accessioned2024-04-24T15:59:28Z
dc.date.available2024-04-24T15:59:28Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractThe fabrication of electro and bioactive surfaces by electrochemical deposition of the thiophene-functionalized polyphenylalanine macromonomer (T-g-PPhe) is reported. The resulting conducting graft copolymer, polythiophene-graft-polyphenylalanine (PT-g-PPhe) formed on the indium tin oxide (ITO) glass surface, is characterized by Fourier transform infrared spectroscopy, scanning electron microscopy, and fluorescence microscopy. Then, possible uses of PT-g-PPhe as matrices in the sensor design for both electrochemical biosensing and cell adhesion studies are investigated. In the first part, PT-g-PPhe that is deposited on ITO is further functionalized with the arginylglycylaspartic acid peptide via 1-Ethyl-3-(3 dimethylaminopropyl) carbodiimide for the selective cell adhesion. Immunofluorescence staining is performed to detect the difference between adherences of integrin alpha v beta 3 receptor positive (U87-MG) and negative (HaCaT) cell lines on to the biofunctional surface. In the second part, an electrochemical glucose sensor is constructed by immobilizing glucose oxidase on the surface of PT-g-PPhe, which is deposited on a glassy carbon electrode.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK) [113Z918]en_US
dc.description.sponsorshipThis work was supported by the Scientific and Technological Research Council of Turkey (TUBITAK, project number 113Z918).en_US
dc.identifier.citationGüler, E., Akbulut, H., Bozokalfa, G., Demir, B., Eyrilmez, G. O., Yavuz, M. ve diğerleri. (2015). Bioapplications of polythiophene-g-polyphenylalanine-covered surfaces. Macromolecular Chemistry and Physics, 216(18), 1868-1878.
dc.identifier.doi10.1002/macp.201500219
dc.identifier.endpage1878en_US
dc.identifier.issn1022-1352
dc.identifier.issn1521-3935
dc.identifier.issue18en_US
dc.identifier.scopus2-s2.0-84941810240
dc.identifier.scopusqualityQ2
dc.identifier.startpage1868en_US
dc.identifier.urihttps://doi.org/10.1002/macp.201500219
dc.identifier.urihttps://hdl.handle.net/11468/14089
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/10.1002/macp.201500219
dc.identifier.volume216en_US
dc.identifier.wosWOS:000362557000004
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorYavuz, Murat
dc.language.isoenen_US
dc.publisherWiley-V C H Verlag Gmbhen_US
dc.relation.ispartofMacromolecular Chemistry and Physics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCell adhesionen_US
dc.subjectElectropolymerizationen_US
dc.subjectGraft copolymeren_US
dc.subjectPolypeptide macromonomeren_US
dc.subjectSurface designen_US
dc.titleBioapplications of polythiophene-g-polyphenylalanine-covered surfacesen_US
dc.titleBioapplications of polythiophene-g-polyphenylalanine-covered surfaces
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
Bioapplications of Polythiophene-g-Polyphenylalanine-Covered Surfaces.pdf
Boyut:
1.15 MB
Biçim:
Adobe Portable Document Format
Açıklama:
Makale Dosyası
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu