Resistin may not associate with gestational diabetes mellitus although insulin resistance

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dc.contributor.authorAkdeniz, N.
dc.contributor.authorKuyumcuoglu, U.
dc.contributor.authorKale, A.
dc.contributor.authorArikan, S.
dc.contributor.authorKale, E.
dc.contributor.authorErdemoglu, M.
dc.date.accessioned2024-04-24T17:37:57Z
dc.date.available2024-04-24T17:37:57Z
dc.date.issued2011
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: Resistin is a potent regulator of glucose homeostasis which is thought to oppose the action of insulin in peripheral tissues. The aim of this study was to determine changes in resistin levels in gestational diabetes mellitus (GDM). Material and Method: Twenty women with GDM (mean age 32.28 +/- 5.01 years old, and gestational age 32.2 +/- 4.8 weeks) matched with 22 non diabetic pregnant women (NGDM) (mean age 30.30 +/- 4.5 years old, and gestational age 34.8 +/- 3.5 weeks) were included in the study. Body mass index (BMI) was calculated. Serum resistin levels were measured and insulin resistance was calculated with HOMA-IR. The Mann Whitney U test was used for statistical analysis. Results: BMI was 33.8 +/- 6.2 kg/m(2) in the GDM group and 28.4 +/- 6.2 kg/m(2) in the NGDM group (p = 0.04). Serum resistin levels were 8.7 +/- 2.1 ng/ml in the GDM group and 8.1 +/- 2.5 ng/ml in the NGDM group. Mean resistin level was not different between the two groups. HOMA-IR in GDM was higher than in the NGDM group (13.2 +/- 12.2 vs 5.8 +/- 5.1, p = 0.02, respectively). Conclusion: Although mean BMI in GDM was higher than in NGDM and insulin resistance in GDM was more marked than in NGDM, serum resistin levels in GDM were not found to be any different from NGDM.en_US
dc.identifier.endpage238en_US
dc.identifier.issn0390-6663
dc.identifier.issue3en_US
dc.identifier.pmid21995154
dc.identifier.scopus2-s2.0-80054124556
dc.identifier.scopusqualityQ4
dc.identifier.startpage236en_US
dc.identifier.urihttps://hdl.handle.net/11468/21265
dc.identifier.volume38en_US
dc.identifier.wosWOS:000294753300013
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherI R O G Canada, Incen_US
dc.relation.ispartofClinical and Experimental Obstetrics & Gynecology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGestational Diabetes Mellitusen_US
dc.subjectResistinen_US
dc.titleResistin may not associate with gestational diabetes mellitus although insulin resistanceen_US
dc.titleResistin may not associate with gestational diabetes mellitus although insulin resistance
dc.typeArticleen_US

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