A novel predictor of infarct-related artery patency before percutaneous intervention and in-hospital outcomes for ST-segment elevation myocardial infarction patients: serum bilirubin level

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dc.contributor.authorAcet, Halit
dc.contributor.authorErtas, Faruk
dc.contributor.authorAkil, Mehmet Ata
dc.contributor.authorPolat, Nihat
dc.contributor.authorAydin, Mesut
dc.contributor.authorAkyuz, Abdurrahman
dc.contributor.authorAycicek, Hilal
dc.date.accessioned2024-04-24T17:24:54Z
dc.date.available2024-04-24T17:24:54Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractIntroduction: Previous studies have reported a relationship between serum bilirubin levels and coronary artery disease (CAD). However, data are rare up to now regarding the relation of bilirubin levels with infarct-related artery (IRA) patency in the setting of ST-segment elevation myocardial infarction (STEMI). Moreover, previous studies reported that increased bilirubin was related to impaired post-intervention coronary flow. To our knowledge, the association between serum total bilirubin (TB) levels and pre-primary percutaneous coronary intervention (PCl) with patency of IRA flow in STEMI patients has not been investigated. Aim: To evaluate the association of TB with pre-primary PCl, coronary flow and in-hospital major adverse cardiac events (MACE) in patients with STEMI. Material and methods: A total of 360 consecutive patients with STEMI (mean age = 61.4+/-13.7 years) admitted within 12 h from the time of symptom onset were enrolled. Patients were divided into 2 groups based on the serum TB levels. We defined normal flow as pre-PCl TIMI 3 flow, while impaired flow was defined as pre-PCl TIMI 2 flow. Results: Pre-PCl impaired flow was higher in the TB group than pre-PCl normal flow (p < 0.001). In-hospital mortality and MACE were significantly higher in the high TB group (p = 0.002, p < 0.001 respectively). In the receiver operating characteristic curve analysis, TB > 0.825 mg/dl predicted impaired IRA flow before p-PCl with a sensitivity of 79% and specificity of 71%. Conclusions: The TB is an inexpensive and readily available marker for STEMI patients undergoing PCl. It can be used for risk stratification in this patient population.en_US
dc.identifier.doi10.5114/pwki.2014.43513
dc.identifier.endpage97en_US
dc.identifier.issn1734-9338
dc.identifier.issn1897-4295
dc.identifier.issue2en_US
dc.identifier.pmid25061454
dc.identifier.scopus2-s2.0-84904023082
dc.identifier.scopusqualityQ3
dc.identifier.startpage91en_US
dc.identifier.urihttps://doi.org/10.5114/pwki.2014.43513
dc.identifier.urihttps://hdl.handle.net/11468/19874
dc.identifier.volume10en_US
dc.identifier.wosWOS:000338485200005
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTermedia Publishing House Ltden_US
dc.relation.ispartofPostepy W Kardiologii Interwencyjnej
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBilirubinen_US
dc.subjectPercutaneous Coronary Interventionen_US
dc.subjectNovel Predictoren_US
dc.titleA novel predictor of infarct-related artery patency before percutaneous intervention and in-hospital outcomes for ST-segment elevation myocardial infarction patients: serum bilirubin levelen_US
dc.titleA novel predictor of infarct-related artery patency before percutaneous intervention and in-hospital outcomes for ST-segment elevation myocardial infarction patients: serum bilirubin level
dc.typeArticleen_US

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