The effect of platelet-albumin ratio on mortality and morbidity in peptic ulcer perforation

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dc.contributor.authorBilge, Huseyin
dc.contributor.authorBasol, Omer
dc.date.accessioned2024-04-24T17:08:21Z
dc.date.available2024-04-24T17:08:21Z
dc.date.issued2022
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground: The aim of our study was to investigate the prognostic role of platelet/albumin ratio in patients treated under emergency conditions for peptic ulcer perforation (PUP). Methods: A retrospective study involving emergency patients who were operated for PUP was carried out. The patients were divided into 2 groups: PUP patients who died after surgical treatment (PUP-M) and PUP patients who survived after surgical treatment (PUP-S). The laboratory values of the patients were compared statistically. A P value of Results: This cohort study consisted of 171 patients treated between June 2013 and December 2019. The mean age of the patients was 46.3 +/- 20.5 years; and 33 (19.3%) patients were women. The age (P <= .001), platelet/lymphocyte ratio (P = .02), lactic dehydrogenase to albumin ratio (P <= .001), and platelet/albumin ratio (PAR; P <= .001) values were high and lymphocyte count was low (P = .006) in the PUP-M group. A positive correlation was determined between length of stay in hospital and age (P <= .001), lactic dehydrogenase/albumin ratio (P <= .001), platelet count (P = .044), and PAR (P <= .001). A substantial negative correlation was determined between length of stay in hospital and albumin count (P <= .001). Conclusions: We determined a high preoperative PAR level in PUP patients who had undergone surgery as a negative prognostic parameter. PAR is a candidate biomarker for clinical practice.en_US
dc.identifier.doi10.1097/MD.0000000000029582
dc.identifier.issn0025-7974
dc.identifier.issn1536-5964
dc.identifier.issue31en_US
dc.identifier.pmid35945802
dc.identifier.scopus2-s2.0-85135733839
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1097/MD.0000000000029582
dc.identifier.urihttps://hdl.handle.net/11468/17308
dc.identifier.volume101en_US
dc.identifier.wosWOS:000837777500068
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofMedicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHospital Mortalityen_US
dc.subjectPeptic Ulcer Perforationen_US
dc.subjectSerum Albuminen_US
dc.titleThe effect of platelet-albumin ratio on mortality and morbidity in peptic ulcer perforationen_US
dc.titleThe effect of platelet-albumin ratio on mortality and morbidity in peptic ulcer perforation
dc.typeArticleen_US

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