Is there an advantage in using low-dose intrathecal bupivacaine for cesarean section?

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dc.contributor.authorTurhanoglu, Selim
dc.contributor.authorKaya, Sedat
dc.contributor.authorErdogan, Hulya
dc.date.accessioned2024-04-24T16:01:56Z
dc.date.available2024-04-24T16:01:56Z
dc.date.issued2009
dc.departmentDicle Üniversitesien_US
dc.description.abstractSpinal anesthesia for cesarean section is associated with a high incidence of maternal hypotension. The aim of this study was to assess the efficacy of low-dose bupivacaine with fentanyl to reduce the incidence of hypotension in spinal anesthesia for cesarean section. Forty pregnant women undergoing elective cesarean section were randomly allocated to two groups; those receiving 10 mg bupivacaine to group B (n = 20) and those receiving 4 mg bupivacaine plus 25 mu g fentanyl to group BF (n = 20); the agents were given intrathecally with patients in the sitting position, with a combined spinal-epidural technique. Sensory block was adequate for surgery in all patients. Hypotension occurred in all patients in group B (100%) and in 15 patients in group BF (75%). The incidence of hypotension, number of ephedrine treatments, and need for ephedrine were significantly greater in group B than group BF. Three patients in group BF required i.v. fentanyl supplementation after delivery. In 1 of these patients, i.v. fentanyl was not adequate, and epidural supplementation of 1% lidocaine was required. The development of hypotension after spinal block in subjects undergoing cesarean section was not prevented despite low-dose (4 mg) bupivacaine plus 25 mu g fentanyl, but the severity of maternal hypotension, and the number of ephedrine treatments and the total dose of ephedrine were decreased.en_US
dc.identifier.doi10.1007/s00540-009-0750-7
dc.identifier.endpage357en_US
dc.identifier.issn0913-8668
dc.identifier.issue3en_US
dc.identifier.pmid19685114
dc.identifier.scopus2-s2.0-69049097246
dc.identifier.scopusqualityQ1
dc.identifier.startpage353en_US
dc.identifier.urihttps://doi.org/10.1007/s00540-009-0750-7
dc.identifier.urihttps://hdl.handle.net/11468/14502
dc.identifier.volume23en_US
dc.identifier.wosWOS:000269011200007
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringer Tokyoen_US
dc.relation.ispartofJournal of Anesthesia
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAnalgesics, Fentanylen_US
dc.subjectLocal Anesthetics, Bupivacaineen_US
dc.subjectAnesthetic Techniques, Spinalen_US
dc.subjectCesarean Sectionen_US
dc.subjectComplication, Hypotensionen_US
dc.titleIs there an advantage in using low-dose intrathecal bupivacaine for cesarean section?en_US
dc.titleIs there an advantage in using low-dose intrathecal bupivacaine for cesarean section?
dc.typeArticleen_US

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