Impact of nutritional assessment on long-term outcomes in patients with carotid artery stenting

dc.authorid0000-0002-9049-7123en_US
dc.authorid0000-0003-2243-6190en_US
dc.contributor.authorDemir, Muhammed
dc.contributor.authorÖzbek, Mehmet
dc.date.accessioned2021-08-16T07:32:45Z
dc.date.available2021-08-16T07:32:45Z
dc.date.issued2021en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Kardiyoloji Ana Bilim Dalıen_US
dc.description.abstractBackground and Aims Malnutrition is associated with poor clinical outcomes in many diseases. The Controlling Nutritional Status (CONUT) is an objective index used for evaluating nutritional status of hospitalised patients. The aim of this study was to investigate the relationship between malnutrition assessed by CONUT score and the prognosis in patients undergoing carotid artery stenting (CAS). Methods and Results The study included 170 patients who underwent CAS because of symptomatic or asymptomatic severe carotid artery stenosis. Median follow-up period was 50 (interquartile range [IQR], 41-60) months. Patients were divided into two groups according to the CONUT score as normal CONUT (score <2) and mild-severe CONUT (score >= 2). Primary endpoint was accepted as MACE (major adverse cardiac events) including all-cause death and ischaemic stroke. The prevalence of MACE was significantly higher in the mild-severe CONUT score group (P = .001). Kaplan Meier analysis showed lower survival rates in the mild-severe CONUT score group (log rank = 9.36, P = .002; Figure 5). The Cox regression analysis showed that, the CONUT score was associated with increased risk of MACE for both unadjusted model and age- and gender- adjusted model, while in a full adjusted model the best predictor was age. Conclusion Higher CONUT scores were associated with adverse outcomes in patients with CAS. Malnutrition assessed by the CONUT score is preferable with regards to the detection of MACE in patients with CAS. Larger studies are warranted to investigate if our preliminary findings translate into clinical outcomes in patients with CAS.en_US
dc.identifier.citationDemir, M. ve Özbek, M. (2021). Impact of nutritional assessment on long-term outcomes in patients with carotid artery stenting. International Journal of Clinical Practice, Early accessen_US
dc.identifier.doi10.1111/ijcp.14637
dc.identifier.issn1368-5031
dc.identifier.issn1742-1241
dc.identifier.pmid34310821
dc.identifier.scopus2-s2.0-85111838994
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/epdf/10.1111/ijcp.14637
dc.identifier.urihttps://hdl.handle.net/11468/7309
dc.identifier.volumeEarly accessen_US
dc.identifier.wosWOS:000679931000001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorDemir, Muhammed
dc.institutionauthorÖzbek, Mehmet
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofInternational Journal of Clinical Practice
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBody-Mass Indexen_US
dc.subjectCardiovascular Eventsen_US
dc.subjectPrognostic impacten_US
dc.subjectEndarterectomyen_US
dc.subjectSurvivalen_US
dc.subjectMalnutritionen_US
dc.subjectDiseaseen_US
dc.subjectStrokeen_US
dc.titleImpact of nutritional assessment on long-term outcomes in patients with carotid artery stentingen_US
dc.titleImpact of nutritional assessment on long-term outcomes in patients with carotid artery stenting
dc.typeArticleen_US

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