Evaluation of Hematological Parameters After Transcatheter Aortic Valve Replacement

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dc.contributor.authorKarahan, Mehmet Zulkuf
dc.contributor.authorAktan, Adem
dc.contributor.authorGuzel, Tuncay
dc.contributor.authorKilic, Raif
dc.contributor.authorGunlu, Serhat
dc.contributor.authorDemir, Muhammed
dc.contributor.authorErtas, Faruk
dc.date.accessioned2024-04-24T17:14:32Z
dc.date.available2024-04-24T17:14:32Z
dc.date.issued2023
dc.departmentDicle Üniversitesien_US
dc.description.abstractAlthough transcatheter aortic valve replacement (TAVR) is safe and effective, mortality and bleeding events post procedure are important. The present study investigated the changes in hematologic parameters to evaluate whether they predict mortality or major bleeding. We enrolled 248 consecutive patients (44.8% male; mean age 79.0 +/- 6.4 years) undergoing TAVR. In addition to demographic and clinical examination, blood parameters were recorded before TAVR, at discharge, 1 month and 1 year. Hemoglobin levels before TAVR 12.1 +/- 1.8 g/dL, 10.8 +/- 1.7 g/dL at discharge, 11.7 +/- 1.7 g/dL at first month, 11.8 +/- 1.4 g/dL at first year (Hemoglobin values compared with pre-TAVR, P < .001, P = .019, P = .047, respectively). Mean platelet volume (MPV) before TAVR 8.72 +/- 1.71 fL, 8.16 +/- 1.46 fL at discharge, 8.09 +/- 1.44 fL at first month, 7.94 +/- 1.18 fL at first year (MPV values compared with pre-TAVR, P < .001, P < .001, P < .001, respectively). Other hematologic parameters were also evaluated. Hemoglobin, platelet count, MPV, and red cell distribution width before the procedure, at discharge, and at the first year did not predict mortality and major bleeding in receiver operating characteristic analysis. After multivariate Cox regression analysis, hematologic parameters were not independent predictors of in-hospital mortality, major bleeding, and death at 1 year after TAVR.en_US
dc.identifier.doi10.1177/00033197231177397
dc.identifier.issn0003-3197
dc.identifier.issn1940-1574
dc.identifier.pmid37236655
dc.identifier.scopus2-s2.0-85163027281
dc.identifier.scopusqualityQ2
dc.identifier.urihttps://doi.org/10.1177/00033197231177397
dc.identifier.urihttps://hdl.handle.net/11468/18036
dc.identifier.wosWOS:001002856000001
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSage Publications Incen_US
dc.relation.ispartofAngiology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAortic Stenosisen_US
dc.subjectHematologic Parametersen_US
dc.subjectTranscatheter Aortic Valve Implantationen_US
dc.subjectMean Platelet Volumeen_US
dc.subjectRed Cell Distribution Widthen_US
dc.subjectHemoglobinen_US
dc.titleEvaluation of Hematological Parameters After Transcatheter Aortic Valve Replacementen_US
dc.titleEvaluation of Hematological Parameters After Transcatheter Aortic Valve Replacement
dc.typeArticleen_US

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