Diagnostic accuracy of mean platelet volume in thromboangiitis obliterans

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dc.contributor.authorYavuz, Celal
dc.contributor.authorCaliskan, Ahmet
dc.contributor.authorKarahan, Oguz
dc.contributor.authorDemirtas, Sinan
dc.contributor.authorYazici, Suleyman
dc.date.accessioned2024-04-24T17:14:44Z
dc.date.available2024-04-24T17:14:44Z
dc.date.issued2014
dc.departmentDicle Üniversitesien_US
dc.description.abstractThromboangiitis obliterans (TAO) affects small-and medium-sized vessels of the extremities via a non-atherosclerotic inflammatory process in the elderly. Although diagnostic criteria have been determined, only a few studies have been described in the laboratory features. Diagnostic biomarkers are important for reducing disruptions caused by TAO. The diagnostic importance of mean platelet volume (MPV) was investigated in TAO patients. Forty-four patients diagnosed with TAO (study group) and 45 healthy individuals (control group) were included in the study. The age, gender and complete blood parameters obtained via peripheral venous blood samples were compared between the two groups. A receiver operating characteristic (ROC) curve was used for determining the diagnostic accuracy of the MPV variable. All the variables were statistically similar in each group except MPV and platelet counts. MPV was significantly higher and platelet count was significantly lower in the TAO group (P < 0.05). In addition, diagnostic accuracy was measured by the area under the ROC curve (Figure 1), and MPV differs significantly (P < 0.001), with a value of 0.783 (95% CI: 0.711-0.854). This study indicates that MPV is probably an important diagnostic predictor in TAO patients. Detection of blood parameters such as platelet properties is important for meticulous care of these patients.en_US
dc.identifier.doi10.1177/1708538112473978
dc.identifier.endpage45en_US
dc.identifier.issn1708-5381
dc.identifier.issn1708-539X
dc.identifier.issue1en_US
dc.identifier.pmid23512907
dc.identifier.scopus2-s2.0-84898920380
dc.identifier.scopusqualityQ2
dc.identifier.startpage42en_US
dc.identifier.urihttps://doi.org/10.1177/1708538112473978
dc.identifier.urihttps://hdl.handle.net/11468/18168
dc.identifier.volume22en_US
dc.identifier.wosWOS:000331145200006
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofVascular
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectThromboangiitis Obliteransen_US
dc.subjectMean Platelet Volumeen_US
dc.subjectDiagnosisen_US
dc.subjectBiomarkeren_US
dc.titleDiagnostic accuracy of mean platelet volume in thromboangiitis obliteransen_US
dc.titleDiagnostic accuracy of mean platelet volume in thromboangiitis obliterans
dc.typeArticleen_US

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