Van yöresinde insan ve köpeklerde toxocariasis’in yayılışı
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Tarih
2012
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Kafkas Üniversitesi Veteriner Fakültesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Bu araştırma, Van yöresinde ELISA yöntemi ile Toxocara canis’in insanlardaki seroprevalansını ve köpeklerde bağırsak parazitlerinin yaygınlığını saptamak amacıyla yapıldı. Araştırma Eylül 2005-Eylül 2007 tarihleri arasında yürütüldü. Çalışma kapsamına, Yüzüncü Yıl Üniversitesi Araştırma Hastanesinin değişik polikliniklerinde muayene edilen eozinofili, ürtiker ve karın ağrısı gibi şikâyetleri olan 800 hasta ile kontrol grubu olarak sağlıklı görünümlü 100 kişi alındı. Hastalar ve kontrol grubunu oluşturan kişilerden alınan kan örneklerinde eozinofil ve total IgE düzeyleri ve ELISA yöntemiyle T. canis seropozitifliği araştırıldı; dışkı örnekleri ise nativ-Lugol, trichrome boyama ve formol-eter çöktürme yöntemleri ile incelendi. Ayrıca 420 köpekten dışkı örneği alınarak makroskobik olarak, nativ-Lugol, modifiye asit-fast boyama ve yüzdürme yöntemleri ile T. canis ve diğer bağırsak parazitleri araştırıldı. İnsanların %15.25’inde toxocariasis pozitifliği, %13.88’inde ise bağırsak parazitleri saptandı. Hastaların %25’inde eozinofili ve bu hastaların ise %28.05’inde toxocariasis pozitifliği belirlendi. Toxocariasis’li hastaların %32.78’inde ürtiker, %22.13’ünde kaşıntı, %9.83’ünde ise karın ağrısı saptandı. Köpeklerin %63.10’unda bir ya da daha çok sayıda bağırsak paraziti bulunmuş olup, T.canis’e %19.05 oranında rastlandı. İnsanlarda toxocariasis ile kırsal alanda ikamet etme (P<0.01), eozinofili (P<0.001), yaşın artması (P<0.001) ve IgE yüksekliği (P<0.001) arasında ayrı ayrı anlamlı ilişkiler saptandı. Van yöresinde insan ve köpeklerde toxocariasis’e sık rastlandığı ve bu hastalıktan korunmak için tedbirlerin alınması gerektiği ve insanlarda bu hastalığın teşhisi için ELISA yönteminin rutin tanı testleri arasına alınmasının gerekli olduğu kanaatine varıldı.
This investigation was performed to detect the seroprevalence of Toxocara canis in humans by ELISA and distribution of intestinal parasites in dogs in Van province. The study was carried out between 2005-2007 Septembers. Eight hundred patients with complaints such as abdominal pain, hypereosinophilia and urticaria who were inspected in various outpatients’ clinics of the Research Hospital of Yüzüncü Yıl University and 100 healthy individuals as control group were investigated. T. canis seropositivity by ELISA, eosinophil counts and total IgE levels were investigated in blood samples received from patients and control group individuals; stool samples of persons were also examined with native-Lugol, trichrome staining and formalin-ether sedimentation methods. Besides, the stool samples of 420 dogs were also taken for the investigation of intestinal parasites. The stools of the dogs were examined for T. canis and other intestinal parasites macroscopically, by native-Lugol, modified acid-fast staining and flotation methods. It was detected toxocariasis seropositivity in 15.25% and intestinal parasites in 13.88% of human. It was determined the eosinophilia in 25% of patients and toxocariasis seropositive in 28.05% of these patients. It was detected urticaria in 32.78%, pruritus in 22.13% and abdominal pain in 9.83% of patients with toxocariasis. One or more intestinal parasites were founded in 63.10% of the dogs, and T. canis was encountered as 19.05%. Positive relationship was detected among toxocariasis and living in rural area (P<0.01), eosinophilia (P<0.001), ageing (P<0.001) and high level of IgE (P<0.001). It was concluded that, toxocariasis is frequently encountered in humans and animals in Van province, measures should be taken to prevent this disease and ELISA method should be take place between routine diagnostic tests for diagnosis of this disease in human.
This investigation was performed to detect the seroprevalence of Toxocara canis in humans by ELISA and distribution of intestinal parasites in dogs in Van province. The study was carried out between 2005-2007 Septembers. Eight hundred patients with complaints such as abdominal pain, hypereosinophilia and urticaria who were inspected in various outpatients’ clinics of the Research Hospital of Yüzüncü Yıl University and 100 healthy individuals as control group were investigated. T. canis seropositivity by ELISA, eosinophil counts and total IgE levels were investigated in blood samples received from patients and control group individuals; stool samples of persons were also examined with native-Lugol, trichrome staining and formalin-ether sedimentation methods. Besides, the stool samples of 420 dogs were also taken for the investigation of intestinal parasites. The stools of the dogs were examined for T. canis and other intestinal parasites macroscopically, by native-Lugol, modified acid-fast staining and flotation methods. It was detected toxocariasis seropositivity in 15.25% and intestinal parasites in 13.88% of human. It was determined the eosinophilia in 25% of patients and toxocariasis seropositive in 28.05% of these patients. It was detected urticaria in 32.78%, pruritus in 22.13% and abdominal pain in 9.83% of patients with toxocariasis. One or more intestinal parasites were founded in 63.10% of the dogs, and T. canis was encountered as 19.05%. Positive relationship was detected among toxocariasis and living in rural area (P<0.01), eosinophilia (P<0.001), ageing (P<0.001) and high level of IgE (P<0.001). It was concluded that, toxocariasis is frequently encountered in humans and animals in Van province, measures should be taken to prevent this disease and ELISA method should be take place between routine diagnostic tests for diagnosis of this disease in human.
Açıklama
Anahtar Kelimeler
İnsan, Köpek, Prevalans, Toxocariasis, Van, Human, Dog, Prevalance, Turkey
Kaynak
Kafkas Üniversitesi Veteriner Fakültesi Dergisi
WoS Q Değeri
Q3
Scopus Q Değeri
Cilt
18
Sayı
4
Künye
Çiçek, M. ve Yılmaz, H. (2012). Van yöresinde insan ve köpeklerde toxocariasis’in yayılışı. Kafkas Üniversitesi Veteriner Fakültesi Dergisi, 18(4), 531-536.
