The association between depression and vitamin D and parathyroid hormone levels in adolescents

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dc.authorid0000-0002-5299-9480en_US
dc.authorid0000-0002-9377-6750en_US
dc.contributor.authorKarabel, Müsemma
dc.contributor.authorŞimşek, Şeref
dc.contributor.authorHaspolat, Yusuf Kenan
dc.contributor.authorKelekçi, Selvi
dc.contributor.authorKarabel, Duran
dc.contributor.authorTuncel, Tuba
dc.contributor.authorŞen, Velat
dc.contributor.authorUluca, Ünal
dc.contributor.authorTan, İlhan
dc.contributor.authorŞahin, Cahit
dc.date.accessioned2021-12-03T10:42:58Z
dc.date.available2021-12-03T10:42:58Z
dc.date.issued2016en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractBackground: Depression, a challenging disorder, affects 1–6% of adolescents and early onset often predicts more serious manifestations in later life. Elevated Parathyroid hormone (PTH), parathormone levels have reported among adults with depression. In this study, the roles of 25(OH) D (vitamin D) and parathormone during adolescence, in which the frequency of depression is high, were studied. Materials and Methods: Patients who were followed-up jointly at both clinics and whose 25(OH) D and PTH levels were evaluated and questioned "Depression Scale for Children" for depression at the same time, were included in the study. Cases’ socio-demographic data, 25(OH) D and PTH levels and Depression Scale’ scores were recorded. Results: Depression was diagnosed in 35 (25.3%) of the 138 patients. No differences were found between vitamin D and parathormone in terms of age and gender in groups either with or without depression. Negative correlation was found between the vitamin D levels and depression score in the group with depression (r=-0.368; P=0.03). A significant and positive correlation was found between the PTH levels and depression score (r=0.399; P=0.018). A significant and negative correlation was found between 25(OH) D and PTH levels. Conclusion: Even if clinical depression is absent, the frequency of depressive symptoms is increased with decreased vitamin D levels and increased PTH levels, independent of other factors. The prevention of depression, specifically in adolescents, is important to decrease possible suicidal and homicidal thoughts that might arise during adulthood, and substance abuse. Maintaining vitamin D support during adolescence, as with the first year of life, is necessary for both the prevention and treatment of depression.en_US
dc.identifier.citationKarabel, M., Şimşek, Ş., Haspolat, Y. K., Kelekçi, S., Karabel, D., Tuncel, T. ve diğarleri. (2016). The association between depression and vitamin D and parathyroid hormone levels in adolescents. International Journal of Pediatrics, 4(2), 1365-1372.en_US
dc.identifier.doi10.22038/IJP.2016.6463
dc.identifier.endpage1372en_US
dc.identifier.issn2345-5047
dc.identifier.issn2345-5055
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85007227169
dc.identifier.scopusqualityN/A
dc.identifier.startpage1365en_US
dc.identifier.urihttps://ijp.mums.ac.ir/article_6463_7ddc8adf12f95b3a84be461eb762f724.pdf
dc.identifier.urihttps://hdl.handle.net/11468/8350
dc.identifier.volume4en_US
dc.identifier.wosWOS:000370472300008
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorKarabel, Müsemma
dc.institutionauthorŞimşek, Şeref
dc.institutionauthorKelekçi, Selvi
dc.institutionauthorHaspolat, Yusuf Kenan
dc.institutionauthorKarabel, Duran
dc.institutionauthorTuncel, Tuba
dc.institutionauthorŞen, Velat
dc.institutionauthorUluca, Ünal
dc.institutionauthorTan, İlhan
dc.institutionauthorŞahin, Cahit
dc.language.isoenen_US
dc.publisherMashhad University of Medical Sciencesen_US
dc.relation.ispartofInternational Journal of Pediatrics
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAdolescentsen_US
dc.subjectDepressionen_US
dc.subjectVitamin Den_US
dc.subjectParathormoneen_US
dc.subjectPreventionen_US
dc.titleThe association between depression and vitamin D and parathyroid hormone levels in adolescentsen_US
dc.titleThe association between depression and vitamin D and parathyroid hormone levels in adolescents
dc.typeArticleen_US

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