Influence of angiotensin-converting enzyme I/D gene polymorphism on the right ventricular myocardial performance index in patients with a first acute anterior myocardial infarction

dc.contributor.authorOzturk, O
dc.contributor.authorUlgen, MS
dc.contributor.authorTekes, S
dc.contributor.authorOzturk, U
dc.contributor.authorToprak, N
dc.date.accessioned2024-04-24T17:15:02Z
dc.date.available2024-04-24T17:15:02Z
dc.date.issued2005
dc.departmentDicle Üniversitesien_US
dc.description.abstractBackground The genetic influence on the myocardial performance index is uncertain, so the aim of the present study was to determine the effects of polymorphism of the angiotensin-converting enzyme (ACE) gene on the right ventricular myocardial performance index (RVMPI) after a first acute anterior myocardial infarction (MI). Methods and Results The subjects were 116 patients with a first acute anterior MI. Based on the polymorphism of the ACE gene, they were classified into 3 groups: deletion/deletion (DD) genotype (group 1, n=45), insertion/deletion (ID) genotype (group 2, n=58), insertion/insertion (II) genotype (group 3, n=13). Echocardiograms were used to determine the RVMPI, left ventricular myocardial performance index (LVMPI), tricuspid E/A, tricuspid deceleration time and the left ventricular diameter diastolic and diameter systolic (LVDd and LVDs). RVMPl and LVMPI were significantly higher in the ACE DD group. Tricuspid E/A, DT, LVDd and LVDs showed no differences among the 3 groups. Conclusion The ID polymorphism of the ACE gene may affect RVMPI and LVMPI after a first acute anterior MI.en_US
dc.identifier.doi10.1253/circj.69.211
dc.identifier.endpage215en_US
dc.identifier.issn1346-9843
dc.identifier.issn1347-4820
dc.identifier.issue2en_US
dc.identifier.pmid15671615
dc.identifier.scopus2-s2.0-14644408791
dc.identifier.scopusqualityQ1
dc.identifier.startpage211en_US
dc.identifier.urihttps://doi.org/10.1253/circj.69.211
dc.identifier.urihttps://hdl.handle.net/11468/18314
dc.identifier.volume69en_US
dc.identifier.wosWOS:000226647900015
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherJapanese Circulation Socen_US
dc.relation.ispartofCirculation Journal
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAngiotensin-Converting Enzymeen_US
dc.subjectGeneticsen_US
dc.subjectMyocardial Infarctionen_US
dc.subjectMyocardial Performance Indexen_US
dc.titleInfluence of angiotensin-converting enzyme I/D gene polymorphism on the right ventricular myocardial performance index in patients with a first acute anterior myocardial infarctionen_US
dc.titleInfluence of angiotensin-converting enzyme I/D gene polymorphism on the right ventricular myocardial performance index in patients with a first acute anterior myocardial infarction
dc.typeArticleen_US

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