Temperature behaviour studies on antipsychotic drug Olanzapine

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dc.contributor.authorErdamar, Işık Yeşim Dicle
dc.date.accessioned2024-04-24T16:15:35Z
dc.date.available2024-04-24T16:15:35Z
dc.date.issued2017
dc.departmentDicle Üniversitesi, Ziya Gökalp Eğitim Fakültesi, Matematik ve Fen Bilimleri Eğitimi Bölümüen_US
dc.description.abstractThe antipsychotic drug Olanzapine in powder form was Co-60 gamma irradiated to investigate in various temperature value. The Electron Paramagnetic Resonance (EPR) spectrum of the irradiated Olanzapine, characterized by g = 2.0030, exhibits an intensity distribution 1:2:1. The room temperature EPR spectra of gamma irradiated Olanzapine was recorded in DMSO solution at frozen state. Temperature behavior of Olanzapine discussed by means of similarities and differences of EPR parameters. Kinetic decay features of radicals induced by gamma irradiation of Olanzapine were also studied. EPR experiments indicated that Olanzapine contained stable free radical species after irradiation and the intensity of the signal is increasing with the absorbed doses suggesting increasing radical concentration in the system. (C) 2017 Elsevier B.V. All rights reserved.en_US
dc.description.sponsorshipResearch Fund of Dicle University (DUBAP) [14 ZEF 147]en_US
dc.description.sponsorshipThis work was supported by Grant No. 14 ZEF 147 of Research Fund of Dicle University (DUBAP).en_US
dc.identifier.citationErdamar, I. Y. D. (2017). Temperature behaviour studies on antipsychotic drug Olanzapine. Journal of Molecular Structure, 1149, 196-198.
dc.identifier.doi10.1016/j.molstruc.2017.07.043
dc.identifier.endpage198en_US
dc.identifier.issn0022-2860
dc.identifier.issn1872-8014
dc.identifier.scopus2-s2.0-85026663658
dc.identifier.scopusqualityQ1
dc.identifier.startpage196en_US
dc.identifier.urihttps://doi.org/10.1016/j.molstruc.2017.07.043
dc.identifier.urihttps://hdl.handle.net/11468/15861
dc.identifier.volume1149en_US
dc.identifier.wosWOS:000413387300021
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofJournal of Molecular Structure
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntipsychotic drugen_US
dc.subjectEpren_US
dc.subjectGamma irradiationen_US
dc.subjectKineticsen_US
dc.titleTemperature behaviour studies on antipsychotic drug Olanzapineen_US
dc.titleTemperature behaviour studies on antipsychotic drug Olanzapine
dc.typeArticleen_US

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