Increased echocardiographic epicardial fat thickness is related to impaired diurnal blood pressure profiles

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dc.contributor.authorErtas, Faruk
dc.contributor.authorKaya, Hasan
dc.contributor.authorAcet, Halit
dc.contributor.authorCil, Habib
dc.contributor.authorAkyuz, Abdurrahman
dc.contributor.authorIslamoglu, Yahya
dc.contributor.authorTekbas, Ebru
dc.date.accessioned2024-04-24T17:20:26Z
dc.date.available2024-04-24T17:20:26Z
dc.date.issued2012
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective. Epicardial fat has been proposed as a new cardiometabolic risk factor. Although epicardial fat thickness (EFT) is associated with hypertension, the relationship between diurnal blood pressure profiles and EFT is still unknown. The purpose of this study is to investigate the association between the echocardiographic EFT and diurnal blood pressure profiles in hypertensive patients. Methods. After the ambulatory blood pressures of 123 patients were monitored, they were divided into three groups according to the clinical diagnoses: 41 patients (33.3%) were in the normotensive group, 40 patients (32.5%) were in the dipper hypertensive group and 42 patients (34.1%) were in the non-dipper hypertensive group. All participants underwent transthoracic echocardiography and ambulatory blood pressure monitoring to measure the EFT and blood pressure responses. Results. The mean EFT measurements of the dipper group were significantly higher than the normotensive group (6.5 +/- 0.6 vs 5.8 +/- 0.6; p < 0.0001). On the other hand, the mean EFTs of the non-dipper group were also significantly higher than the dipper group (7.4 +/- 0.7 vs 6.5 +/- 0.6, p < 0.0001). An EFT of >= 7 mm predicted the non-dipper profile in hypertensive patients with 74% sensitivity and 71% specificity (receiving operator characteristic area under the curve: 0.826, 95% CI 0.738-0.913; p < 0.0001). EFT was associated with both dipper (OR 8.9, 95% CI 3.03-26.3; p < 0.0001) and non-dipper blood pressure profiles (OR 12.3, 95% CI 1.75-86.31; p < 0.0001), and this relationship was also independent from all the risk factors. Conclusion. Echocardiographic EFT assessment is independently associated with impaired diurnal blood pressure profiles in the hypertensive individuals. Thus, the echocardiographic assessment of the EFT may be helpful in cardiometabolic risk stratification and therapeutic interventions.en_US
dc.identifier.doi10.3109/08037051.2011.649538
dc.identifier.endpage208en_US
dc.identifier.issn1651-1999
dc.identifier.issue3en_US
dc.identifier.pmid22229446
dc.identifier.scopus2-s2.0-84860867653
dc.identifier.scopusqualityQ2
dc.identifier.startpage202en_US
dc.identifier.urihttps://doi.org/10.3109/08037051.2011.649538
dc.identifier.urihttps://hdl.handle.net/11468/19055
dc.identifier.volume21en_US
dc.identifier.wosWOS:000303831700010
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofBlood Pressure
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDipperen_US
dc.subjectEchocardiographyen_US
dc.subjectEpicardial Fat Thicknessen_US
dc.subjectHypertensionen_US
dc.subjectNon-Dipperen_US
dc.titleIncreased echocardiographic epicardial fat thickness is related to impaired diurnal blood pressure profilesen_US
dc.titleIncreased echocardiographic epicardial fat thickness is related to impaired diurnal blood pressure profiles
dc.typeArticleen_US

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