Effect of exercise on colorectal cancer prevention and treatment

dc.authorid0000000308820524en_US
dc.contributor.authorOruç, Zeynep
dc.contributor.authorKaplan, Muhammet Ali
dc.date.accessioned2021-09-15T05:58:30Z
dc.date.available2021-09-15T05:58:30Z
dc.date.issued2019en_US
dc.departmentDicle Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıklar Ana Bilim Dalıen_US
dc.description.abstractIn recent years, because of improved cancer screening, detection and treatment modalities, a rapid increase in the population of colorectal and other cancer survivors has been observed. The increasing population has justified the requirement of preventive strategies such as lifestyle modifications with regard to obesity, physical activity, diet and smoking. Physical activity may prevent approximately 15% of the colon cancers. Furthermore, several observational studies have demonstrated the efficacy and dose-dependent and anti-cancer effects of exercise on decreasing the mortality and risk of recurrence before and after the colorectal cancer (CRC) diagnosis. However, the required exercise dose, type and intensity are yet unclear. The results of randomised prospective studies are expected to determine the optimal amount, type and intensity of exercise and formulate the most appropriate exercise plan and guidelines, according to the requirements and comorbidities of the patients. In addition, recent studies have focused on the molecular and genetic mechanisms underlying the effect of physical activity on disease outcomes and recurrence rates. This review aimed to investigate the effects of physical activity and the biological basis of these effects in preventing the risk and recurrence of CRC and decreasing the hazards of cancer and cancer treatment.en_US
dc.identifier.citationOruç, Z. ve Kaplan, M. A. (2019). Effect of exercise on colorectal cancer prevention and treatment. World Journal of Gastrointestinal Oncology, 11(5), 348-366.en_US
dc.identifier.doi10.4251/wjgo.v11.i5.348
dc.identifier.endpage366en_US
dc.identifier.issn1948-5204
dc.identifier.issue5en_US
dc.identifier.pmid31139306
dc.identifier.scopus2-s2.0-85066802907
dc.identifier.scopusqualityQ2
dc.identifier.startpage348en_US
dc.identifier.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522766/
dc.identifier.urihttps://hdl.handle.net/11468/7585
dc.identifier.volume11en_US
dc.identifier.wosWOS:000468152700001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorKaplan, Muhammet Ali
dc.language.isoenen_US
dc.publisherBaishideng Publishing Group Coen_US
dc.relation.ispartofWorld Journal of Gastrointestinal Oncology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectColorectal canceren_US
dc.subjectExerciseen_US
dc.subjectPhysical activityen_US
dc.titleEffect of exercise on colorectal cancer prevention and treatmenten_US
dc.titleEffect of exercise on colorectal cancer prevention and treatment
dc.typeArticleen_US

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