Incidence of occult leiomyosarcoma in presumed morcellation cases: a database study

Basit Öğe Kaydı
dc.contributor.authorRodriguez, Ana M.
dc.contributor.authorAsoglu, Mehmet R.
dc.contributor.authorSak, Muhammet Erdal
dc.contributor.authorTan, Alai
dc.contributor.authorBorahay, Mostafa A.
dc.contributor.authorKilic, Gokhan S.
dc.date.accessioned2024-04-24T16:11:20Z
dc.date.available2024-04-24T16:11:20Z
dc.date.issued2016
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective: Our objective was to estimate the incidence of uterine leiomyosarcoma in patients with leiomyomas following laparoscopic supracervical hysterectomy and myomectomy procedures. Study design: For this study, we analyzed records of 13,964 women aged 25-64 years who underwent laparoscopic supracervical hysterectomies or myomectomies for leiomyomas from 2002 to 2011 using Clinformatics DataMart. Patient records were divided into two groups: history of laparoscopic supracervical hysterectomy and history of myomectomy. Subjects were tracked to identify diagnosis of leiomyosarcoma within 1 year of the procedure. We analyzed data from the 25-39, 40-49, and 50-64 age brackets. Evidence was obtained from a cohort study from national private insurance claims in the US. Results: Our results showed the incidence of occult leiomyosarcoma developing within 1 year following supracervical hysterectomy using a laparoscopic-assisted approach are 9.8, 10.7, and 33.4 per 10,000 for the 25-39, 40-49, and 50-64 age brackets, respectively; the overall incidence rate is 13.1 per 10,000. The incidence rate of occult leiomyosarcoma developing within 1 year following myomectomy using a laparoscopic-assisted approach are 0.0, 33.8, and 90.1 per 10,000 for the 25-39, 40-49, and 50-64 age brackets, respectively; the overall incidence rate is 17.3 per 10,000. Conclusion: Our analysis shows the overall risk of being diagnosed with occult leiomyosarcoma is 12.9 per 10,000 in laparoscopic-assisted supracervical hysterectomy and myomectomy for patients younger than 49. There is no evidence of occult leiomyosarcoma 1 year after operation for patients younger than 40 who underwent laparoscopic myomectomy. (C) 2015 Published by Elsevier Ireland Ltd.en_US
dc.description.sponsorshipNCATS NIH HHS [UL1 TR001439, UL1 TR000071] Funding Source: Medlineen_US
dc.identifier.doi10.1016/j.ejogrb.2015.11.009
dc.identifier.endpage35en_US
dc.identifier.issn0301-2115
dc.identifier.issn1872-7654
dc.identifier.pmid26699101
dc.identifier.scopus2-s2.0-84960126395
dc.identifier.scopusqualityQ2
dc.identifier.startpage31en_US
dc.identifier.urihttps://doi.org/10.1016/j.ejogrb.2015.11.009
dc.identifier.urihttps://hdl.handle.net/11468/15358
dc.identifier.volume197en_US
dc.identifier.wosWOS:000371187300007
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofEuropean Journal of Obstetrics & Gynecology and Reproductive Biology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectLeiomyomaen_US
dc.subjectLeiomyosarcomaen_US
dc.subjectIncidenceen_US
dc.subjectLaparoscopyen_US
dc.titleIncidence of occult leiomyosarcoma in presumed morcellation cases: a database studyen_US
dc.titleIncidence of occult leiomyosarcoma in presumed morcellation cases: a database study
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu