Chemical profile, antioxidant and enzyme inhibition activities of natural Saudi sidr and talh honeys

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dc.contributor.authorAl Qahtani, Hayfa W. S.
dc.contributor.authorYagi, Sakina
dc.contributor.authorYılmaz, Mustafa Abdullah
dc.contributor.authorÇakır, Oğuz
dc.contributor.authorTarhan, Abbas
dc.contributor.authorMustafa, Ahmed Ali
dc.contributor.authorZengin, Gokhan
dc.contributor.orcid0000-0002-4090-7227
dc.contributor.orcid0000-0002-8006-2054
dc.contributor.orcid0000-0001-6548-7823
dc.date.accessioned2024-04-24T15:59:21Z
dc.date.available2024-04-24T15:59:21Z
dc.date.issued2022
dc.departmentDicle Üniversitesi, Eczacılık Fakültesi, Temel Eczacılık Bilimleri Bölümü, Analitik Kimya Ana Bilim Dalıen_US
dc.description.abstractHoney is used since ancient time as a food and to cure many diseases. The present study investigated the chemical constituents, antioxidant and enzyme inhibition activities of natural Saudi Sidr (SH) and Talh (TH) honeys. Beside entire honey samples, ethyl acetate, ethanol and water extracts were prepared. The total polyphenolic content of SH, TH and their extracts was in the range of 2.86-7.21 and 3.80-17.33 mg gallic acid equivalents/g, respectively and the total flavonoids content was in the range of 0.05-1.17 and 0.18-2.38 mg rutin equivalents/g, respectively. Out of the 53 standards analyzed by HPLC, 27 compounds were detected with highest number of compounds identified in the ethyl acetate extract of TH (45 %, 24/53) and SH (26 %, 14/53), respectively. Quinic acid was dominant compound identified in all honey samples with the highest content determined in TH ethanol extract (4454 mu g/g). The majority of tested samples possessed considerable anti-radicals and reducing ions capacity with the ethyl acetate extract from TH exerted significantly (p<0.05) the highest activity. All honey samples did not show chelating iron metal property. Honey samples revealed variable enzyme inhibition activity with TH (entire and/or ethyl acetate extract) showed significantly (p<0.05) the highest acetylcholinesterase, butyrylcholinesterase, tyrosinase and alpha-amylase inhibition activity. In conclusion, ethyl acetate is the best solvent for extraction of bioactive molecules from the two honey types. Moreover, the dark-colored TH contained the highest number of molecules and consequently exerted the best antioxidant and enzyme inhibition activities in most assays.en_US
dc.identifier.citationAl Qahtani, H. W. S., Yagi, S., Yılmaz, M. A., Çakır, O., Tarhan, A., Mustafa, A. A. ve diğerleri. (2022). Chemical profile, antioxidant and enzyme inhibition activities of natural Saudi sidr and talh honeys. Chemistry and Biodiversity, 19(7), 1-10.
dc.identifier.doi10.1002/cbdv.202200227
dc.identifier.endpage10
dc.identifier.issn1612-1872
dc.identifier.issn1612-1880
dc.identifier.issue7en_US
dc.identifier.pmid35608187
dc.identifier.scopus2-s2.0-85131900663
dc.identifier.scopusqualityQ3
dc.identifier.startpage1
dc.identifier.urihttps://doi.org/10.1002/cbdv.202200227
dc.identifier.urihttps://hdl.handle.net/11468/14003
dc.identifier.urihttps://onlinelibrary.wiley.com/doi/10.1002/cbdv.202200227
dc.identifier.volume19en_US
dc.identifier.wosWOS:000811078200001
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.institutionauthorYılmaz, Mustafa Abdullah
dc.institutionauthorÇakır, Oğuz
dc.institutionauthorTarhan, Abbas
dc.language.isoenen_US
dc.publisherWiley-V C H Verlag Gmbhen_US
dc.relation.ispartofChemistry & Biodiversity
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSidr honeyen_US
dc.subjectTalh honeyen_US
dc.subjectChemical profileen_US
dc.subjectAntioxidant activityen_US
dc.subjectEnzyme inhibition activityen_US
dc.titleChemical profile, antioxidant and enzyme inhibition activities of natural Saudi sidr and talh honeysen_US
dc.titleChemical profile, antioxidant and enzyme inhibition activities of natural Saudi sidr and talh honeys
dc.typeArticleen_US

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