Serum total oxidant and antioxidant status in earthquake survivors with post-traumatic stress disorder

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dc.contributor.authorOzdemir, Pinar Guzel
dc.contributor.authorKaplan, Ibrahim
dc.contributor.authorUysal, Cem
dc.contributor.authorBulut, Mahmut
dc.contributor.authorAtli, Abdullah
dc.contributor.authorBez, Yasin
dc.contributor.authorKaya, Mehmet Cemal
dc.date.accessioned2024-04-24T16:19:01Z
dc.date.available2024-04-24T16:19:01Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractObjective Oxidative stress has been shown to play an important role in the pathogenesis of post-traumatic stress disorder (PTSD). Although there are some studies on oxidative stress and PTSD, there is no report available on the serum total oxidant and antioxidant status in earthquake survivors with PTSD. Therefore, this study aimed to investigate the serum total oxidant and antioxidant status in earthquake survivors with chronic PTSD. Material and Methods The study group included 45 earthquake survivors with PTSD and 40 earthquake survivors without PTSD. The oxidative status was determined using the total antioxidant status and total oxidant status (TOS) measurements and by calculating the oxidative stress index (OSI). Results There were no statistically significant differences in the total antioxidant status, TOS, or OSI when comparing individuals with and without PTSD (all, p>0.05). There were no correlations between Clinician-Administered PTSD Scale scores and oxidant and antioxidant stress markers (all, p>0.05). Conclusions Our results suggest that the total oxidant and antioxidant status may not affect earthquake survivors with PTSD. This is the first study to evaluate the oxidative status in earthquake survivors with PTSD. Further studies are necessary to confirm these findings.en_US
dc.identifier.doi10.1017/neu.2014.47
dc.identifier.endpage158en_US
dc.identifier.issn1601-5215
dc.identifier.issue3en_US
dc.identifier.pmid25597474
dc.identifier.scopus2-s2.0-84929297072
dc.identifier.scopusqualityQ1
dc.identifier.startpage153en_US
dc.identifier.urihttps://doi.org/10.1017/neu.2014.47
dc.identifier.urihttps://hdl.handle.net/11468/16373
dc.identifier.volume27en_US
dc.identifier.wosWOS:000354391600003
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherCambridge Univ Pressen_US
dc.relation.ispartofActa Neuropsychiatrica
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEarthquake Survivorsen_US
dc.subjectOxidative Stress Indexen_US
dc.subjectPost-Traumatic Stress Disorderen_US
dc.subjectTotal Antioxidant Statusen_US
dc.subjectTotal Oxidant Statusen_US
dc.titleSerum total oxidant and antioxidant status in earthquake survivors with post-traumatic stress disorderen_US
dc.titleSerum total oxidant and antioxidant status in earthquake survivors with post-traumatic stress disorder
dc.typeArticleen_US

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