Value of Platelet Indices in Identifying Complete Resolution of Thrombus in Deep Venous Thrombosis Patients

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dc.contributor.authorSevuk, Utkan
dc.contributor.authorAltindag, Rojhat
dc.contributor.authorBahadir, Mehmet Veysi
dc.contributor.authorAy, Nurettin
dc.contributor.authorDemirtas, Ertan
dc.contributor.authorAyaz, Firat
dc.date.accessioned2024-04-24T16:02:47Z
dc.date.available2024-04-24T16:02:47Z
dc.date.issued2015
dc.departmentDicle Üniversitesien_US
dc.description.abstractWe aimed to evaluate whether mean platelet volume (MPV) and platelet distribution width (PDW) are helpful to identify complete thrombus resolution (CTR) after acute deep venous thrombosis (DVT). Patients who had first-time episode of acute proximal DVT were included in this retrospective study. 100 patients with DVT were divided into two groups according to absence (group 1; n = 68) or presence (group 2; n = 32) of CTR on doppler ultrasonography at month 6. There were no significant difference in admission MPV and PDW levels between group 1 and group 2. MPV (p = 0.03) and PDW (p < 0.001) levels at month 6 were significantly higher in group 1 than in group 2. CTR showed a moderate negative correlation with PDW at month 6 (rho = -0.47) and a weak negative correlation with MPV at month 6 (rho = -0.26). Logistic regression analysis showed that PDW (OR, 2.2; p = 0.004) at month 6 was an independent risk factor for the presence of residual venous thrombosis in DVT patients. Receiver operating characteristics analysis revealed that a 8.4 % decrease in admission MPV at month 6 provided 62 % sensitivity and 62 % specificity (AUC: 0.64) and a 15.4 % decrease in admission PDW at month 6 provided 87 % sensitivity and 94 % specificity (AUC: 0.89) for prediction of CTR in DVT patients. Percent change in admission MPV and PDW levels at month 6 may be used to identify the patients with CTR after a first episode of acute proximal DVT.en_US
dc.identifier.doi10.1007/s12288-014-0365-5
dc.identifier.endpage76en_US
dc.identifier.issn0971-4502
dc.identifier.issn0974-0449
dc.identifier.issue1en_US
dc.identifier.pmid25548449
dc.identifier.scopus2-s2.0-84943588738
dc.identifier.scopusqualityQ3
dc.identifier.startpage71en_US
dc.identifier.urihttps://doi.org/10.1007/s12288-014-0365-5
dc.identifier.urihttps://hdl.handle.net/11468/14916
dc.identifier.volume31en_US
dc.identifier.wosWOS:000346904000013
dc.identifier.wosqualityQ4
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoenen_US
dc.publisherSpringer Indiaen_US
dc.relation.ispartofIndian Journal of Hematology and Blood Transfusion
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDeep Venous Thrombosisen_US
dc.subjectComplete Thrombus Resolutionen_US
dc.subjectMean Platelet Volumeen_US
dc.subjectPlatelet Distribution Widthen_US
dc.titleValue of Platelet Indices in Identifying Complete Resolution of Thrombus in Deep Venous Thrombosis Patientsen_US
dc.titleValue of Platelet Indices in Identifying Complete Resolution of Thrombus in Deep Venous Thrombosis Patients
dc.typeArticleen_US

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